BS9228

antibody from Bioworld Technology, Inc
Targeting: TOLLIP IL-1RAcPIP
Provider product page for BS9228
Western blot
Immunohistochemistry

Antibody data

Product number
BS9228 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Tollip (W151) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 120-168 of Human Tollip.
Description
Tollip (toll-interacting protein) serves as a suppressor of innate immunity signaling and links the serine/threonine kinase IRAK to the IL-1 receptor complex upon receptor activation. Overexpression of Tollip in HEK-293 cells inhibits NF°ÙB activation in response to TLR2 and TLR4 signaling. Negative regulation of TLR signaling by Tollip may limit the production of proinflammatory mediators during inflammation and infection. Tollip forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. The Tollip protein shows ubiquitous expression in mouse.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TOLLIP protein structure - BS9228 shown in red.