24168-1-AP

antibody from Proteintech Group

Targeting: XBP1 XBP2

Provider product page for 24168-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [25]
Comments [0]
Validations
Western blot [1]

Submit

Product number: 24168-1-AP - Provider product page
Provider: Proteintech Group
Product name: XBP1S/XBP1U antibody
Antibody type: Polyclonal
Description: XBP1S/XBP1U antibody (Cat. #24168-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

XBP1 protein structure - 24168-1-AP shown in red.

Submitted references X-Box Binding Protein 1 Regulates Osteogenesis of Periodontal Ligament Cells During Aging by Modulating P53 Signaling Pathway.

Zheng Y, Zhai M, Bai X, Yu K, Li J, Zhang Z
Stem cells international 2026;2026:2846096

Endothelial KSR2 regulated by genetic variation protects against atherosclerosis through AMPKα1 stabilization.

Liu M, Fu X, Zhang H, Pan J, Jia Q, Zhang C, An F
Theranostics 2026;16(5):2598-2626

Echinacoside regulates the IRE1/XBP1 signaling pathway through HSP72 to reduce endoplasmic reticulum stress and improve diabetic kidney disease.

Geng R, Ma C, Wen L, Dai W, Liu J, Yang J, Hu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158062

Akkermansia muciniphila alleviates experimental colitis through FXR-mediated repression of unspliced XBP1.

Bu F, Zhang K, Song B, He L, Lu Z, Yuan X, Chen C, Jiang F, Tao Y, Zhang W, Zhang D, Chen Y, Wang Q
mSystems 2026 Feb 17;11(2):e0158925

Quercetin as a Novel Antidepressant: Mechanistic Insights into Its Neuroprotective and Anti-inflammatory Effects.

Fan X, Wang Z, Sun L, Qin Y, Liu Y, Wu S, Du L
Molecular neurobiology 2025 Nov 24;63(1):155

ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.

Liang H, Zhang C, Hu M, Hu F, Wang S, Wei W, Hu W
Molecular carcinogenesis 2025 Jan;64(1):57-71

A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2.

Gan L, Jiang Q, Huang D, Wu X, Zhu X, Wang L, Xie W, Huang J, Fan R, Jing Y, Tang G, Li XD, Guo J, Yin S
Nature chemical biology 2025 Jan;21(1):80-90

HSPA12B Protects Against Age-Related Endothelial Cell Senescence by Regulating STING Degradation.

Li T, Zhu P, Adams J, Tu F, Wang J, Garbe C, Dalal S, Singh K, Zhang X, Liu L, Williams DL, Li C, Wang X
Aging cell 2025 Dec;24(12):e70260

Targeting the SYVN1-EGFR axis: a breakthrough strategy for TKI-resistant NSCLC.

Xie X, Tong W, Xie Y, Jiang H, Jiang A, Huang J, Liu Z, Yu J
Cell death & disease 2025 Aug 28;16(1):655

GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.

Mou L, Sun D, Qu J, Tan X, Wang S, Zeng Q, Liu C
Journal of hazardous materials 2024 Sep 5;476:135101

Apelin‑13 reduces high glucose‑induced mitochondrial dysfunction in cochlear hair cells by inhibiting endoplasmic reticulum stress.

Huo Z, Gu J, He T
Experimental and therapeutic medicine 2024 May;27(5):226

Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice.

Liu L, Wu J, Zhang C, Cao T, Lu Y, He Z, Li Z
Brain research 2024 Jul 15;1835:148930

Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway.

Geng Q, Wu W, Yang M, Gu F, Cai W, Qin Y, Wei L, Wang H, Li N
Heliyon 2024 Dec 30;10(24):e39987

XBP1s activates METTL3/METTL14 for ER-phagy and paclitaxel sensitivity regulation in breast cancer.

Wang J, Fan P, Shen P, Fan C, Zhao P, Yao Shen, Dong K, Ling R, Chen S, Zhang J
Cancer letters 2024 Aug 1;596:216846

Transcriptomics analysis of LINC02202/XBP1 axis in melanoma: Implications for drug targeting and PD-1 monoclonal antibody efficacy.

Shang Y, Yang H, Cui J, Wang L, Wang L, Wang Y, Zhao MM, Yu PY, Qiao H, Yang WJ
Journal of cellular and molecular medicine 2024 Apr;28(8):e18247

Network pharmacology, molecular docking, and in vitro experimental verification of the mechanism of Guanxining in treating diabetic atherosclerosis.

Wang W, Wang S, Li Y, Zhu M, Xu Q, Luo B, Liu Y, Liu Y
Journal of ethnopharmacology 2024 Apr 24;324:117792

Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.

Sheng B, Wang W, Xia D, Qu X
BMC pharmacology & toxicology 2023 Sep 22;24(1):45

IKVAV peptide-containing hydrogel decreases fibrous scar after spinal cord injury by inhibiting fibroblast migration and activation.

Jiang T, Li S, Xu B, Liu K, Qiu T, Dai H
Behavioural brain research 2023 Oct 18;455:114683

Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation.

Yu J, Shen S, Yan Y, Liu L, Luo R, Liu S, Wu Y, Li Y, Jiang J, Ying H
Nutrients 2023 Feb 9;15(4)

Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing.

Dou Z, Li B, Wu L, Qiu T, Wang X, Zhang X, Shen Y, Lu M, Yang Y
ACS applied materials & interfaces 2023 Feb 8;15(5):6297-6311

Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.

Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737

Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure.

Yang X, Yu X, Zhao Z, He Y, Zhang J, Su X, Sun N, Fan Z
Journal of Zhejiang University. Science. B 2021 Sept 15;22(9):746-756

Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.

Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209

Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.

Huang Y, Lin Q, Huo Z, Chen C, Zhou S, Ma X, Gao H, Lin Y, Li X, He J, Zhang P, Liu C
Journal of virology 2020 Nov 9;94(23)

24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death.

Urano Y, Ho Vo DK, Hirofumi A, Noguchi N
Cell death discovery 2019;5:113

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The XBP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human XBP1. This antibody recognizes human antigen. The XBP1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 24168-1-AP.pdf

: Show more