24868-1-AP

antibody from Proteintech Group

Targeting: XBP1 XBP2

Provider product page for 24868-1-AP

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Immunohistochemistry

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Antigen structure
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Product number: 24868-1-AP - Provider product page
Provider: Proteintech Group
Product name: XBP1S-specific antibody
Antibody type: Polyclonal
Description: KD/KO validated XBP1S-specific antibody (Cat. #24868-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

XBP1 protein structure - 24868-1-AP shown in red.

Submitted references Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.

Liu J, Xu L, Wang L, Wang Q, Yu L, Zhang S
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956

4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis.

Xiong F, Wang C, Lu J, Bai G, Zhou D, Ling J
Experimental neurology 2024 May;375:114738

Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes.

Zhu L, Shi Y, Feng Z, Yuan D, Guo S, Wang Y, Shen H, Li Y, Yan F, Wang Y
European journal of pharmacology 2024 May 15;971:176519

The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells.

Zhang C, Huang X, Xie B, Lian D, Chen J, Li W, Lin Y, Cai X, Li J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116268

X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity.

Hong Y, Zhou X, Li Q, Chen J, Wei Y, Long C, Shen L, Zheng X, Li D, Wang X, Yu C, Wu S, Wei G
Genes & diseases 2024 Mar;11(2):935-951

Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke.

Xie J, Zhang Y, Li B, Xi W, Wang Y, Li L, Liu C, Shen L, Han B, Kong Y, Yao H, Zhang Z
Journal of translational medicine 2024 Mar 7;22(1):248

Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression.

Ma J, Tan J, Zhang W, Bai M, Liu K
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):88

Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders.

Zhang Y, Chen L, Xuan Y, Zhang L, Tian W, Zhu Y, Wang J, Wang X, Qiu J, Yu J, Tang M, He Z, Zhang H, Chen S, Shen Y, Wang S, Zhang R, Xu L, Ma X, Liao Y, Hu C
Cell reports 2024 Mar 26;43(3):113900

The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.

Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466

ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.

Qian H, Zhao Y, Wang Y, Zhao H, Cui J, Wang Z, Ye H, Fang X, Ge Z, Zhang Y, Ye L
Toxicology 2024 Jan;501:153696

Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.

Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39

Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice.

Li X, Pan Y, Liu K, Yang Y, Ye Y, Xu Q, Fan M, Guo F
Cellular signalling 2024 Jan;113:110929

Tumorous IRE1α facilitates CD8(+)T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma.

Yang Y, Wang S, Wang XX, Guo S, Wang H, Shi Q, Tian Y, Wang H, Zhao T, Zhang H, Zhang B, Gao T, Li C, Yi X, Guo W
Cell communication and signaling : CCS 2024 Jan 30;22(1):83

A nanoemulsion targeting adipose hypertrophy and hyperplasia shows anti-obesity efficiency in female mice.

Lu Y, Luo Z, Zhou H, Shi Y, Zhu Y, Guo X, Huang J, Zhang J, Liu X, Wang S, Shan X, Yin H, Du Y, Li Q, You J, Luo L
Nature communications 2024 Jan 2;15(1):72

ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression.

Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, D'Orazi G, Cirone M
Autophagy 2024 Aug;20(8):1854-1867

Up-regulation of HSP90α in HDM-induced asthma causes pyroptosis of airway epithelial cells by activating the cGAS-STING-ER stress pathway.

Huang H, Qiao Y, Chu L, Ye C, Lin L, Liao H, Meng X, Zou F, Zhao H, Zou M, Cai S, Dong H
International immunopharmacology 2024 Apr 20;131:111917

Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response.

Luo R, Wei Y, Chen P, Zhang J, Wang L, Wang W, Wang P, Tian W
Stem cells international 2023;2023:4483776

Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines.

Jiao B, Zhang M, Zhang C, Cao X, Liu B, Li N, Sun J, Zhang X
PeerJ 2023;11:e15219

Obesity impacts placental function through activation of p-IRE1a-XBP1s signaling.

Shen WB, Wang B, Yao R, Goetzinger KR, Wu S, Gao H, Yang P
Frontiers in cell and developmental biology 2023;11:1023327

Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.

Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811

Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.

Erzurumlu Y, Muhammed MT
Cellular signalling 2023 Sep;109:110745

Preparation of a new resource food-arabinogalactan and its protective effect against enterotoxicity in IEC-6 cells by inhibiting endoplasmic reticulum stress.

Zhang S, Wang S, Fan YY, Liu WC, Zheng YN, Wang Z, Ren S, Li W
International journal of biological macromolecules 2023 Sep 30;249:126124

The UFMylated ribosome-recognition protein SAYSD1 is predominantly expressed in spermatids but is dispensable for fertility in mice.

Chang L, Fujii W, Yogo K
Biochemical and biophysical research communications 2023 Sep 24;674:102-108

UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.

Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221

LIMK1 m(6)A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.

Chen L, Sun K, Qin W, Huang B, Wu C, Chen J, Lai Q, Wang X, Zhou R, Li A, Liu S, Zhang Y
Cancer letters 2023 Nov 1;576:216420

Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy.

Dowdell A, Marsland M, Faulkner S, Gedye C, Lynam J, Griffin CP, Marsland J, Jiang CC, Hondermarck H
FASEB bioAdvances 2023 May;5(5):211-220

Genomic targets of the IRE1-XBP1s pathway in mediating metabolic adaptation in epithelial plasticity.

Qiao D, Skibba M, Xu X, Brasier AR
Nucleic acids research 2023 May 8;51(8):3650-3670

Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.

Zheng Y, Dai H, Chen R, Zhong Y, Zhou C, Wang Y, Zhan C, Luo J
Journal of cellular physiology 2023 Mar;238(3):582-596

1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.

Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577

Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.

Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H
NPJ Parkinson's disease 2023 Mar 7;9(1):35

Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.

Erzurumlu Y, Catakli D, Dogan HK
Journal of natural medicines 2023 Jun;77(3):572-583

Coumarin-Based Fluorescent Inhibitors for Photocontrollable Bioactivation.

Ren F, Zhu W, Yang S, Zhang C, Hou Y, Li R, Wen J, Zou LH, Gao M, Wang WL, Wu Z, Shao A
Molecular pharmaceutics 2023 Jun 5;20(6):3223-3233

Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.

Erzurumlu Y, Dogan HK, Cataklı D
Steroids 2023 Jul;195:109238

Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop.

Qiu W, Guo Q, Guo X, Wang C, Li B, Qi Y, Wang S, Zhao R, Han X, Du H, Zhao S, Pan Z, Fan Y, Wang Q, Gao Z, Li G, Xue H
Journal of nanobiotechnology 2023 Jul 22;21(1):233

Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.

Erzurumlu Y, Dogan HK, Catakli D
Molecular biology reports 2023 Feb;50(2):1253-1265

Endoplasmic reticulum stress promotes endometrial fibrosis through the TGF-β/SMAD pathway.

Bao M, Feng Q, Zou L, Huang J, Zhu C, Xia W
Reproduction (Cambridge, England) 2023 Feb 1;165(2):171-182

Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway.

Ding L, Zhu H, Wang K, Huang R, Yu W, Yan B, Zhou B, Wang H, Yang Z, Liu Z, Wang J
Environmental science and pollution research international 2023 Dec;30(60):125790-125805

Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.

Lu D, Liu Y, Huang H, Hu M, Li T, Wang S, Shen S, Wu R, Cai W, Lu T, Lu Z
Translational stroke research 2023 Dec;14(6):910-928

An investigation of the endoplasmic reticulum stress in obesity exposure in the prenatal period.

Tüfekci KK, Tatar M, Terzi F, Bakirhan EG
Journal of chemical neuroanatomy 2023 Dec;134:102348

ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.

Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)

XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.

Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139

Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.

Liu Z, Nan P, Gong Y, Tian L, Zheng Y, Wu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114897

Tissue Proteogenomic Landscape Reveals the Role of Uncharacterized SEL1L3 in Progression and Immunotherapy Response in Lung Adenocarcinoma.

Shen CY, Chang WH, Chen YJ, Weng CW, Regmi P, Kier MKK, Su KY, Chang GC, Chen JS, Chen YJ, Yu SL
Journal of proteome research 2023 Apr 7;22(4):1056-1070

Drp1-Mediated Mitochondrial Metabolic Dysfunction Inhibits the Tumor Growth of Pituitary Adenomas.

Fan K, Ding X, Zang Z, Zhang Y, Tang X, Pei X, Chen Q, Yin H, Zheng X, Chen Y, Li S, Yang H
Oxidative medicine and cellular longevity 2022;2022:5652586

Deletion of ACLY Disrupts Histone Acetylation and IL-10 Secretion in Trophoblasts, Which Inhibits M2 Polarization of Macrophages: A Possible Role in Recurrent Spontaneous Abortion.

Chen X, Song QL, Li ZH, Ji R, Wang JY, Ge C, Xiao ZN, Guo DY, Yang J
Oxidative medicine and cellular longevity 2022;2022:5216786

Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.

Hu H, Luo Z, Liu X, Huang L, Lu X, Ding R, Duan C, He Y
International journal of endocrinology 2022;2022:2009753

Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.

Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348

Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca(2+) axis.

Jing G, Zuo J, Fang Q, Yuan M, Xia Y, Jin Q, Liu Y, Wang Y, Zhang Z, Liu W, Wu X, Song X
Journal of neuroinflammation 2022 Sep 28;19(1):237

Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.

Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970

Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.

Liu P, Zu F, Chen H, Yin X, Tan X
Cellular & molecular biology letters 2022 Oct 8;27(1):87

Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy.

Zhang R, Lin H, You Q, Zhang Z, Bai L, Chen F, Zhu X, Zhang Z, Li Y
Journal of virology 2022 Oct 26;96(20):e0137522

CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.

Liu Y, Huang Y, Zhang X, Ma X, He X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Cells 2022 Nov 26;11(23)

The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.

Yu W, Xu G, Chen H, Xiao L, Liu G, Hu P, Li S, Kasim V, Zeng C, Tong X
Acta pharmaceutica Sinica. B 2022 May;12(5):2315-2329

Targeting X box-binding protein-1 (XBP1) enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide- α methyl ester-mediated photodynamic therapy.

Yu H, Zhang Y, Zuo Q, Zhong S, Chen Y, Zhang M, Zhan F, Ou Y
Photodiagnosis and photodynamic therapy 2022 Mar;37:102646

Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways.

Miyahara H, Hasegawa K, Yashiro M, Ohara T, Fujisawa M, Yoshimura T, Matsukawa A, Tsukahara H
Scientific reports 2022 Mar 21;12(1):4819

ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress.

Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, Di Renzo L, D'Orazi G, Cirone M
Cell death discovery 2022 Jun 25;8(1):295

Neuronal microRNAs safeguard ER Ca(2+) homeostasis and attenuate the unfolded protein response upon stress.

Paschou M, Papazafiri P, Charalampous C, Zachariadis M, Dedos SG, Doxakis E
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):373

The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.

Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biochemical and biophysical research communications 2022 Jul 12;613:19-25

Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic Hedgehog pathway in cerebral infarction.

Hui Z, Wang S, Li J, Wang J, Zhang Z
Journal of ethnopharmacology 2022 Jan 30;283:114634

Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.

Shi C, Pei M, Wang Y, Chen Q, Cao P, Zhang L, Guo J, Deng W, Wang L, Li X, Gong Z
Biochemical and biophysical research communications 2022 Feb 26;594:1-7

Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin.

Wang J, Ding L, Wang K, Huang R, Yu W, Yan B, Wang H, Zhang C, Yang Z, Liu Z
Ecotoxicology and environmental safety 2022 Aug;241:113772

Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.

Huang Z, Gan S, Zhuang X, Chen Y, Lu L, Wang Y, Qi X, Feng Q, Huang Q, Du B, Zhang R, Liu Z
Cells 2022 Aug 9;11(16)

Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas.

Benedetti R, Arena A, Romeo MA, Gilardini Montani MS, Gonnella R, Santarelli R, Trivedi P, Cirone M
International journal of molecular sciences 2022 Aug 14;23(16)

Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.

Sun J, Chen W, Li S, Yang S, Zhang Y, Hu X, Qiu H, Wu J, Xu S, Chu T
Frontiers in pharmacology 2021;12:751845

Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.

Tan X, Cai D, Chen N, Du S, Qiao D, Yue X, Wang T, Li J, Xie W, Wang H
Toxicology letters 2021 Oct 10;350:98-110

Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes.

Tong X, Stein R
Diabetes 2021 Nov;70(11):2595-2607

The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization.

Li W, Wang Y, Zhu L, Du S, Mao J, Wang Y, Wang S, Bo Q, Tu Y, Yi Q
Journal of cellular and molecular medicine 2021 Jul;25(14):6709-6720

Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.

Li J, Xie J, Wang YZ, Gan YR, Wei L, Ding GW, Ding YH, Xie DX
Molecular medicine reports 2021 Feb;23(2)

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.

Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477

Hydrogen sulphide reduces hyperhomocysteinaemia-induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis.

Jiang S, Xu W, Chen Z, Cui C, Fan X, Cai J, Gong Y, Geng B
Journal of cellular and molecular medicine 2021 Apr;25(7):3437-3448

Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress.

Mai X, Yin X, Chen P, Zhang M
Frontiers in pharmacology 2020;11:574229

Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.

Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, Wang D, Lao L, Lin X, Wei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375

Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.

Huang Y, Lin Q, Huo Z, Chen C, Zhou S, Ma X, Gao H, Lin Y, Li X, He J, Zhang P, Liu C
Journal of virology 2020 Nov 9;94(23)

Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.

Yuan F, Jiang H, Yin H, Jiang X, Jiao F, Chen S, Ying H, Chen Y, Zhai Q, Guo F
Nature communications 2020 Jun 5;11(1):2847

Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).

Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438

The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.

Wang G, Zhou P, Chen X, Zhao L, Tan J, Yang Y, Fang Y, Zhou J
Cancer biology & therapy 2017 Aug 3;18(8):584-595

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