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LearnNB110-81601
antibody from Novus Biologicals
Targeting: TRPM2
EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- NB110-81601 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-81601, RRID:AB_1147355
- Product name
- Rabbit Polyclonal TRPM2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This is specific for isoform 1, or the long isoform (TRPM2-L), of TRPM2.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone.
ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells.
The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia.
Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.
TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.
TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.
Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.
Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture.
Yee AG, Freestone PS, Bai JZ, Lipski J
Experimental neurology 2017 Jan;287(Pt 1):34-43
Experimental neurology 2017 Jan;287(Pt 1):34-43
ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells.
Rah SY, Kwak JY, Chung YJ, Kim UH
Scientific reports 2015 Mar 25;5:9482
Scientific reports 2015 Mar 25;5:9482
The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia.
Chung MK, Asgar J, Lee J, Shim MS, Dumler C, Ro JY
Neuroscience 2015 Jun 25;297:160-9
Neuroscience 2015 Jun 25;297:160-9
Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.
Lu S, Xiang L, Clemmer JS, Mittwede PN, Hester RL
Microcirculation (New York, N.Y. : 1994) 2014 Nov;21(8):754-60
Microcirculation (New York, N.Y. : 1994) 2014 Nov;21(8):754-60
TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.
Roberge S, Roussel J, Andersson DC, Meli AC, Vidal B, Blandel F, Lanner JT, Le Guennec JY, Katz A, Westerblad H, Lacampagne A, Fauconnier J
Cardiovascular research 2014 Jul 1;103(1):90-9
Cardiovascular research 2014 Jul 1;103(1):90-9
TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.
Melzer N, Hicking G, Göbel K, Wiendl H
PloS one 2012;7(10):e47617
PloS one 2012;7(10):e47617
Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.
Chung KK, Freestone PS, Lipski J
Journal of neurophysiology 2011 Dec;106(6):2865-75
Journal of neurophysiology 2011 Dec;106(6):2865-75
Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture.
Bai JZ, Lipski J
Neurotoxicology 2010 Mar;31(2):204-14
Neurotoxicology 2010 Mar;31(2):204-14
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRPM2 Antibody [NB110-81601] - Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured) Photo courtesy of Dr. Paco Herson, Oregon Health & Science University.
