BS7930

antibody from Bioworld Technology, Inc
Targeting: TRPM2 EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7
Provider product page for BS7930
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7930 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TRPM2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TRPM2.
Description
Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TRPM2 protein structure - BS7930 shown in red.