ABIN351193
antibody from antibodies-online
Targeting: TRPM2
EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7
Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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- Product number
- ABIN351193 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN351193, RRID:AB_10784991
- Product name
- anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2) (4th Cytoplasmic Domain) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the 4th cytoplasmic domain of human TRPM2 (TRPC7, LTRPC2) conjugated to an immunogenic carrier protein was used as the immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- 4th Cytoplasmic Domain
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death.
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
Immunocyte Ca2+ influx system mediated by LTRPC2.
The DNA sequence of human chromosome 21.
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain.
Zhang W, Chu X, Tong Q, Cheung JY, Conrad K, Masker K, Miller BA
The Journal of biological chemistry 2003 May 2;278(18):16222-9
The Journal of biological chemistry 2003 May 2;278(18):16222-9
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.
Wehage E, Eisfeld J, Heiner I, Jüngling E, Zitt C, Lückhoff A
The Journal of biological chemistry 2002 Jun 28;277(26):23150-6
The Journal of biological chemistry 2002 Jun 28;277(26):23150-6
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.
Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T, Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y
Molecular cell 2002 Jan;9(1):163-73
Molecular cell 2002 Jan;9(1):163-73
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
Perraud AL, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet JP, Scharenberg AM
Nature 2001 May 31;411(6837):595-9
Nature 2001 May 31;411(6837):595-9
Immunocyte Ca2+ influx system mediated by LTRPC2.
Sano Y, Inamura K, Miyake A, Mochizuki S, Yokoi H, Matsushime H, Furuichi K
Science (New York, N.Y.) 2001 Aug 17;293(5533):1327-30
Science (New York, N.Y.) 2001 Aug 17;293(5533):1327-30
The DNA sequence of human chromosome 21.
Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, Taudien S, Blechschmidt K, Polley A, Menzel U, Delabar J, Kumpf K, Lehmann R, Patterson D, Reichwald K, Rump A, Schillhabel M, Schudy A, Zimmermann W, Rosenthal A, Kudoh J, Schibuya K, Kawasaki K, Asakawa S, Shintani A, Sasaki T, Nagamine K, Mitsuyama S, Antonarakis SE, Minoshima S, Shimizu N, Nordsiek G, Hornischer K, Brant P, Scharfe M, Schon O, Desario A, Reichelt J, Kauer G, Blocker H, Ramser J, Beck A, Klages S, Hennig S, Riesselmann L, Dagand E, Haaf T, Wehrmeyer S, Borzym K, Gardiner K, Nizetic D, Francis F, Lehrach H, Reinhardt R, Yaspo ML, Chromosome 21 mapping and sequencing consortium
Nature 2000 May 18;405(6784):311-9
Nature 2000 May 18;405(6784):311-9
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain.
Nagamine K, Kudoh J, Minoshima S, Kawasaki K, Asakawa S, Ito F, Shimizu N
Genomics 1998 Nov 15;54(1):124-31
Genomics 1998 Nov 15;54(1):124-31
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