Antibody data
- Antibody Data
- Antigen structure
- References [31]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 10292-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10292-1-AP, RRID:AB_2069615
- Product name
- calreticulin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated calreticulin antibody (Cat. #10292-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Methionine enkephalin (MENK) suppresses lung cancer by regulating the Bcl-2/Bax/caspase-3 signaling pathway and enhancing natural killer cell-driven tumor immunity.
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Calreticulin as a special marker to distinguish dental pulp stem cells from gingival mesenchymal stem cells.
The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.
Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.
Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality.
Naphthyl quinoxaline thymidine conjugate is a potent anticancer agent post UVA activation and elicits marked inhibition of tumor growth through vaccination.
Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics.
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes.
The multidisciplinary support in preventing alcohol relapse after liver transplantation: A single-center experience.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Combination of CALR and PDIA3 is a potential prognostic biomarker for non-small cell lung cancer.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Identification of low-abundance proteins via fractionation of the urine proteome with weak anion exchange chromatography.
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Lu L, Zhao H, Liu J, Zhang Y, Wang X
BioMed research international 2021;2021:6650181
BioMed research international 2021;2021:6650181
Methionine enkephalin (MENK) suppresses lung cancer by regulating the Bcl-2/Bax/caspase-3 signaling pathway and enhancing natural killer cell-driven tumor immunity.
Zhang S, Liu N, Ma M, Huang H, Handley M, Bai X, Shan F
International immunopharmacology 2021 Sep;98:107837
International immunopharmacology 2021 Sep;98:107837
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Luo L, Qin B, Jiang M, Xie L, Luo Z, Guo X, Zhang J, Li X, Zhu C, Du Y, Peng L, You J
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Jin F, Qi J, Liu D, You Y, Shu G, Du Y, Wang J, Xu X, Ying X, Ji J, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
Calreticulin as a special marker to distinguish dental pulp stem cells from gingival mesenchymal stem cells.
Lei T, Wang J, Liu Y, Chen P, Zhang Z, Zhang X, Wang X, Li Q, Du H
International journal of biological macromolecules 2021 May 1;178:229-239
International journal of biological macromolecules 2021 May 1;178:229-239
The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.
Nguyen DT, Le TM, Hattori T, Takarada-Iemata M, Ishii H, Roboon J, Tamatani T, Kannon T, Hosomichi K, Tajima A, Taniuchi S, Miyake M, Oyadomari S, Tanaka T, Kato N, Saito S, Mori K, Hori O
Scientific reports 2021 Jun 22;11(1):13086
Scientific reports 2021 Jun 22;11(1):13086
Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
Ye J, Qi L, Du Z, Yu L, Chen K, Li R, Feng R, Zhai W
Aging 2021 Feb 11;13(4):5607-5620
Aging 2021 Feb 11;13(4):5607-5620
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Li ST, Huang, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P
Nature metabolism 2020 Mar;2(3):256-269
Nature metabolism 2020 Mar;2(3):256-269
NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.
Jin F, Qi J, Zhu M, Liu D, You Y, Shu G, Du Y, Wang J, Yu H, Sun M, Xu X, Shen Q, Ying X, Ji J, Du Y
ACS applied materials & interfaces 2020 Jul 22;12(29):32372-32387
ACS applied materials & interfaces 2020 Jul 22;12(29):32372-32387
Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality.
Gualerzi A, Kooijmans SAA, Niada S, Picciolini S, Brini AT, Camussi G, Bedoni M
Journal of extracellular vesicles 2019;8(1):1568780
Journal of extracellular vesicles 2019;8(1):1568780
Naphthyl quinoxaline thymidine conjugate is a potent anticancer agent post UVA activation and elicits marked inhibition of tumor growth through vaccination.
Yuan Y, Wang Z, Yang R, Qian T, Zhou Q
European journal of medicinal chemistry 2019 Jun 1;171:255-264
European journal of medicinal chemistry 2019 Jun 1;171:255-264
Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death.
Li W, Yang J, Luo L, Jiang M, Qin B, Yin H, Zhu C, Yuan X, Zhang J, Luo Z, Du Y, Li Q, Lou Y, Qiu Y, You J
Nature communications 2019 Jul 26;10(1):3349
Nature communications 2019 Jul 26;10(1):3349
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
Chen JL, Hung CT, Keller JJ, Lin HC, Wu YJ
BMC ophthalmology 2019 Aug 2;19(1):168
BMC ophthalmology 2019 Aug 2;19(1):168
Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics.
Liu X, Weng Y, Liu P, Sui Z, Zhou L, Huang Y, Zhang L, Zhang Y, Tan X
OncoTargets and therapy 2018;11:3345-3357
OncoTargets and therapy 2018;11:3345-3357
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
Huang H, Zheng X, Cai C, Yao Z, Lu S, Meng X, Miao Y, He Z, Cai C, Zou F
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes.
Lakhter AJ, Pratt RE, Moore RE, Doucette KK, Maier BF, DiMeglio LA, Sims EK
Diabetologia 2018 May;61(5):1124-1134
Diabetologia 2018 May;61(5):1124-1134
The multidisciplinary support in preventing alcohol relapse after liver transplantation: A single-center experience.
Attilia ML, Lattanzi B, Ledda R, Galli AM, Farcomeni A, Rotondo C, Di Gregorio V, Mennini G, Poli E, Attilia F, Ginanni Corradini S, Rossi M, Merli M
Clinical transplantation 2018 May;32(5):e13243
Clinical transplantation 2018 May;32(5):e13243
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Wu Y, Xu X, Ma L, Yi Q, Sun W, Tang L
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
The international journal of biochemistry & cell biology 2017 Sep;90:103-113
Combination of CALR and PDIA3 is a potential prognostic biomarker for non-small cell lung cancer.
Wang K, Li H, Chen R, Zhang Y, Sun XX, Huang W, Bian H, Chen ZN
Oncotarget 2017 Nov 14;8(57):96945-96957
Oncotarget 2017 Nov 14;8(57):96945-96957
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Wu W, Lin C, Wu K, Jiang L, Wang X, Li W, Zhuang H, Zhang X, Chen H, Li S, Yang Y, Lu Y, Wang J, Zhu R, Zhang L, Sui S, Tan N, Zhao B, Zhang J, Li L, Feng D
The EMBO journal 2016 Jul 1;35(13):1368-84
The EMBO journal 2016 Jul 1;35(13):1368-84
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Xie Q, Su J, Jiao B, Shen L, Ma L, Qu X, Yu C, Jiang X, Xu Y, Sun L
International journal of oncology 2016 Dec;49(6):2507-2519
International journal of oncology 2016 Dec;49(6):2507-2519
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Yao W, Fan W, Huang C, Zhong H, Chen X, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 Mar;67(2):140-5
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 Mar;67(2):140-5
Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
Cheng KC, Huang HH, Hung CT, Chen CC, Wu WC, Suen JL, Chen KJ, Wu YJ, Chang CH
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2013 Dec;251(12):2777-87
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2013 Dec;251(12):2777-87
A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
Yang MS, Wang HS, Wang BS, Li WH, Pang ZF, Zou BK, Zhang X, Shi XT, Mu DB, Zhang DX, Gao YS, Sun XW, Xia SJ
Diagnostic pathology 2013 Apr 15;8:58
Diagnostic pathology 2013 Apr 15;8:58
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Deisenroth C, Itahana Y, Tollini L, Jin A, Zhang Y
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
Identification of low-abundance proteins via fractionation of the urine proteome with weak anion exchange chromatography.
Lu CM, Wu YJ, Chen CC, Hsu JL, Chen JC, Chen JY, Huang CH, Ko YC
Proteome science 2011 Apr 8;9:17
Proteome science 2011 Apr 8;9:17
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Yang X, Zou P, Yao J, Yun D, Bao H, Du R, Long J, Chen X
Journal of proteome research 2010 Mar 5;9(3):1402-15
Journal of proteome research 2010 Mar 5;9(3):1402-15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 10292-1-AP(calreticulin antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 10292-1-AP(calreticulin antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The calreticulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human calreticulin. This antibody recognizes human,mouse,rat antigen. The calreticulin antibody has been validated for the following applications: ELISA, WB, IHC analysis.