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- References [153]
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- Product number
- 10292-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10292-1-AP, RRID:AB_2069615
- Product name
- calreticulin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated calreticulin antibody (Cat. #10292-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Self-assembling RADA16-I peptide in situ hydrogel loaded with Celastrol boost immunogenic cell death in oral squamous cell carcinoma.
Targeting ROS-metabolism dual pathways to trigger PANoptosis by cobalt-vanadium oxides biomimetic nanocakes for tumor immunotherapy.
Purification of murine cortex mitochondria using a modified magnetic bead isolation method.
Carboxymethyl chitosan-based injectable hydrogel immobilizing single-atom nanozymes for localized ROS amplification and ferroptosis-enhanced postoperative oral cancer therapy.
A precise theranostic nanoplatform amplifies anti-tumor efficacy via copper ionophores and sonodynamic therapy.
A purpurin-based metalloimmunostimulant amplifies ROS and modulates STING/TNF-α axis to potentiate melanoma immunotherapy.
Antitumor Cytisine-Platinum(IV) Prodrugs Potentiate Crosstalk between Endoplasmic Reticulum and Mitochondria through Calcium Overload Accompanied by Immunogenic Cell Death.
Bioengineered Anti-PD-L1 Functionalized Nanoplatform for Targeted Delivery and Tumor Immune Reprogramming Against Colorectal Cancer.
NIR-Programmed Trimodal Macrophage Nanovectors for Effective Anti-Tumor Therapy in Mice Model.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Identification and comprehensive analysis of an immune-related gene prognostic model for indicating tumor immune microenvironment features in soft tissue sarcoma.
ALKBH5 reverses romidepsin-mediated anti-multiple myeloma activity via regulation of m6A modification of FOXM1.
Dual-mode immunotherapy: ultrasound responsive zinc-based nano-contract agents synergistically activate the GAS-STING pathway for enhanced tumor sono-metalloimmunotherapy.
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
Impact of nanoplastics on thyroid function: Unraveling cellular biokinetics, molecular mechanisms and human risk assessment.
Oncolytic microgels with regulated antibody release augment tumor immunotherapy.
Engineered biomimetic vesicles induce cuproptosis and disrupt efferocytosis for metastatic adenoid cystic carcinoma immunotherapy.
Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carcinoma.
Light-controlled pyroptosis via redox-responsive microneedles enhances photodynamic-epigenetic immunotherapy in breast cancer.
Integrative multi-omics and machine learning identify CALR as a diagnostic and therapeutic target in aneurysmal subarachnoid hemorrhage.
Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.
Microwave-Activated Bacterial Biorobot for Multimodal Cancer Therapy.
Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy.
Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment.
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Metabolic reprogramming nanomedicine potentiates colon cancer sonodynamic immunotherapy by inhibiting the CD39/CD73/ADO pathway.
Piezoelectric-Triggered Ferroptosis for Cancer Therapy via Cascade-Enhanced Immune Response.
Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury.
Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine.
APOL6 as a potential biomarker of immuno-correlation and therapeutic prediction in cancer immunotherapy.
An Implantable Double-Layered Spherical Scaffold Depositing Gene and Cell Agents to Facilitate Collaborative Cancer Immunotherapy.
Compromised efferocytosis during aging is related to COVID-19 severity in mice.
Biomimetic multifunctional nanoparticles for improved radiotherapy and immunotherapy in cancer treatment.
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma.
Starting the Engine and Releasing the Brakes of T-Cell Responses: A Biomimetic Dendritic Cell Nanoplatform for Improved Glioblastoma Immunotherapy.
Hesperidin Derivatives Contained Hydrogel Dressing for Photothermal Treatment of Melanoma and Postoperative Tissue Regeneration.
EndoMAP.v1 charts the structural landscape of human early endosome complexes.
Identification of a Novel Antibacterial Function of Mammalian Calreticulin.
CALR promotes corneal epithelial cell proliferation and migration through Wnt7a.
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor.
EndoMAP.v1, a Structural Protein Complex Landscape of Human Endosomes.
Novel Indoleamine-2,3-Dioxygenase-Targeted Pt(IV) Prodrugs Regulate the Tumor Immune Microenvironment to Achieve Chemoimmunotherapy In Vitro and In Vivo.
Sodium butyrate enhances sorafenib-induced ferroptosis and immunogenic cell death by modulating IRF2-Oasl2-cGAS pathway in colorectal cancer.
Clinically friendly smart hydrogel boosts cuproptosis and PD-L1 upregulation to enhance anti-tumor immunotherapy.
Hypoxic migrasomes drive colorectal cancer liver metastasis by mediating CD5L(+) macrophage efferocytosis via NRP2/PROX1 axis.
An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Harnessing prazosin for tumors: Liposome hybrid nanovesicles activate tumor immunotherapy via autophagy inhibition.
Copper-Induced Cuproptosis and Immunogenic Cell Death Synergize with Radiotherapy and PD-1 Blockade in Osteosarcoma.
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
Responsive plasmonic hybrid nanorods enables metabolism reprogramming via cuproptosis-photothermal combined cancer therapy.
Control Over Kinetic Self-Assembly of Phthalocyanine into Photothermal Nano-Vaccine Enabling Tunable Superlarge Absorption Redshift.
Enhanced cGAS-STING Activation and Immune Response by LPDAM Platform-Based Lapachone-Chemical-Photothermal Synergistic Therapy for Colorectal Cancer.
Chimeric Antigen Receptor-Engineered Cell Membrane-Coated Nanoparticles Promote Dual-Targeted mRNA-Based Cancer Gene Therapy.
Tumor signal amplification and immune decoy strategy using bacterial membrane-coated nanoparticles for immunotherapy.
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Self-assembling chemodrug fiber-hydrogel for transarterial chemoembolization and radiotherapy-enhanced antitumor immunity.
Nanoparticle/Engineered Bacteria Based Triple-Strategy Delivery System for Enhanced Hepatocellular Carcinoma Cancer Therapy.
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Potentiated Calcium Carbonate with Enhanced Calcium Overload Induction and Acid Neutralization Capabilities to Boost Chemoimmunotherapy against Liver Cancer.
Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy.
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Bimetallic peroxide nanoparticles induce PANoptosis by disrupting ion homeostasis for enhanced immunotherapy.
Inhalable metal-organic framework-mediated cuproptosis combined with PD-L1 checkpoint blockade for lung metastasis synergistic immunotherapy.
Enhancing cell pyroptosis with biomimetic nanoparticles for melanoma chemo-immunotherapy.
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Multiple Immunomodulatory Strategies Based on Targeted Regulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Immune Homeostasis against Hepatocellular Carcinoma.
Cu(2)WS(4)-PEG Nanozyme as Multifunctional Sensitizers for Enhancing Immuno-Radiotherapy by Inducing Ferroptosis.
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy.
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
Copper-coordinated nanoassemblies based on photosensitizer-chemo prodrugs and checkpoint inhibitors for enhanced apoptosis-cuproptosis and immunotherapy.
Engineered Microbial Nanohybrids for Tumor-Mediated NIR II Photothermal Enhanced Ferroptosis/Cuproptosis and Immunotherapy.
Thioredoxin domain containing 5 is involved in the hepatic storage of squalene into lipid droplets in a sex-specific way.
Novel Carrier-Free Nanodrug Enhances Photodynamic Effects by Blocking the Autophagy Pathway and Synergistically Triggers Immunogenic Cell Death for the Efficient Treatment of Breast Cancer.
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy.
Proton-Gradient-Driven Porphyrin-Based Liposome Remote-Loaded with Imiquimod as In Situ Nanoadjuvants for Synergistically Augmented Tumor Photoimmunotherapy.
Engineered low-pathogenic Helicobacter pylori as orally tumor immunomodulators for the stimulation of systemic immune response.
Inhalable nanoparticles with enhanced cuproptosis and cGAS-STING activation for synergistic lung metastasis immunotherapy.
Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment.
Multifunctional Nanoplatform-Mediated Chemo-Photothermal Therapy Combines Immunogenic Cell Death with Checkpoint Blockade to Combat Triple-Negative Breast Cancer and Distant Metastasis.
Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles.
Neuroprotective role of calreticulin after spinal cord injury in mice.
Combination of ferroptosis and pyroptosis dual induction by triptolide nano-MOFs for immunotherapy of Melanoma.
Cell type-specific translational regulation by human DUS enzymes.
Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma.
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
Engineered bacteria combined with doxorubicin nanoparticles suppress angiogenesis and metastasis in murine melanoma models.
Downregulation of Calreticulin and Annexin A2 Expression in Acquired Middle Ear Cholesteatoma by 2-DE Analysis.
NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.
ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions.
Rhythm Mild-Temperature Photothermal Therapy Enhancing Immunogenic Cell Death Response in Oral Squamous Cell Carcinoma.
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR.
Biomimetic Prussian blue nanocomplexes for chemo-photothermal treatment of triple-negative breast cancer by enhancing ICD.
Nanointegrative In Situ Reprogramming of Tumor-Intrinsic Lipid Droplet Biogenesis for Low-Dose Radiation-Activated Ferroptosis Immunotherapy.
Improving nanochemoimmunotherapy efficacy by boosting "eat-me" signaling and downregulating "don't-eat-me" signaling with Ganoderma lucidum polysaccharide-based drug delivery.
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block "eat-me" signal.
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Targeted Nanobubbles of PD-L1 mAb Combined with Doxorubicin as a Synergistic Tumor Repressor in Hepatocarcinoma.
Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy.
Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
ER-Targeting PDT Converts Tumors into In Situ Therapeutic Tumor Vaccines.
Combination of oxaliplatin and POM-1 by nanoliposomes to reprogram the tumor immune microenvironment.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Membrane protective role of autophagic machinery during infection of epithelial cells by Candida albicans.
Design and characterization of PROTAC degraders specific to protein N-terminal methyltransferase 1.
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Methionine enkephalin (MENK) suppresses lung cancer by regulating the Bcl-2/Bax/caspase-3 signaling pathway and enhancing natural killer cell-driven tumor immunity.
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Calreticulin as a special marker to distinguish dental pulp stem cells from gingival mesenchymal stem cells.
The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.
Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum.
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.
Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality.
Naphthyl quinoxaline thymidine conjugate is a potent anticancer agent post UVA activation and elicits marked inhibition of tumor growth through vaccination.
Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics.
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes.
The multidisciplinary support in preventing alcohol relapse after liver transplantation: A single-center experience.
Treatment of colon cancer with liver X receptor agonists induces immunogenic cell death.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.
Combination of CALR and PDIA3 is a potential prognostic biomarker for non-small cell lung cancer.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells.
Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats.
Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Identification of low-abundance proteins via fractionation of the urine proteome with weak anion exchange chromatography.
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Zhang C, Wu J, Li H, Shi Y, Liang Y, Chen J, Qin L
Drug delivery and translational research 2026 May;16(5):1372-1387
Drug delivery and translational research 2026 May;16(5):1372-1387
Targeting ROS-metabolism dual pathways to trigger PANoptosis by cobalt-vanadium oxides biomimetic nanocakes for tumor immunotherapy.
Du S, Ma G, Li X, Chao M, Fan L, Zhao Z, Tang R, Li J, Jing C, Liu Y, Yu D, Liu Z, Gao F
Biomaterials 2026 Mar;326:123726
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Purification of murine cortex mitochondria using a modified magnetic bead isolation method.
Josic E, Ujevic A, Puljko B, Maček Hrvat N, Lipovcic A, Kalanj-Bognar S, Mlinac-Jerkovic K
MethodsX 2026 Jun;16:103871
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Carboxymethyl chitosan-based injectable hydrogel immobilizing single-atom nanozymes for localized ROS amplification and ferroptosis-enhanced postoperative oral cancer therapy.
Qi M, Hong Y, Liu Y, Wang H, Xiong Y, Tang Y, Ma M, Gao Z, Zhang D
Carbohydrate polymers 2026 Feb 1;373:124668
Carbohydrate polymers 2026 Feb 1;373:124668
A precise theranostic nanoplatform amplifies anti-tumor efficacy via copper ionophores and sonodynamic therapy.
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Materials today. Bio 2026 Apr;37:102957
Materials today. Bio 2026 Apr;37:102957
A purpurin-based metalloimmunostimulant amplifies ROS and modulates STING/TNF-α axis to potentiate melanoma immunotherapy.
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Materials today. Bio 2026 Apr;37:102804
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Antitumor Cytisine-Platinum(IV) Prodrugs Potentiate Crosstalk between Endoplasmic Reticulum and Mitochondria through Calcium Overload Accompanied by Immunogenic Cell Death.
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Biomaterials research 2025;29:0284
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NIR-Programmed Trimodal Macrophage Nanovectors for Effective Anti-Tumor Therapy in Mice Model.
Xie Y, Shi Y, Li Z, Xu S, Chen Z, Ye X, Yan W
International journal of nanomedicine 2025;20:11295-11314
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Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
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Identification and comprehensive analysis of an immune-related gene prognostic model for indicating tumor immune microenvironment features in soft tissue sarcoma.
Xu S, Liu Y, Cai Q, Sun J, Guan X
Frontiers in oncology 2025;15:1609501
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ALKBH5 reverses romidepsin-mediated anti-multiple myeloma activity via regulation of m6A modification of FOXM1.
Zhang Y, Cao X, Li W, Cui Z, Mao J, Yao R, Liu L
Biochemical pharmacology 2025 Sep;239:116998
Biochemical pharmacology 2025 Sep;239:116998
Dual-mode immunotherapy: ultrasound responsive zinc-based nano-contract agents synergistically activate the GAS-STING pathway for enhanced tumor sono-metalloimmunotherapy.
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Ultrasonics sonochemistry 2025 Sep;120:107494
Ultrasonics sonochemistry 2025 Sep;120:107494
Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson's Disease Model: Transcriptomic Evidence.
Lyu P, Wen F, Fu Z, Li J, Li Q, Cai X, Huang S, Qiu X, Zhang Z, Huang Y, Zhang J
Journal of integrative neuroscience 2025 Sep 18;24(9):40105
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Impact of nanoplastics on thyroid function: Unraveling cellular biokinetics, molecular mechanisms and human risk assessment.
Iglesias-Hernandez P, Tarazona JV, Manosalva J, Megias D, Docando F, Cañas-Portilla AI, Torres-Ruiz M, De la Vieja A
Journal of hazardous materials 2025 Sep 15;498:139890
Journal of hazardous materials 2025 Sep 15;498:139890
Oncolytic microgels with regulated antibody release augment tumor immunotherapy.
Guo J, Tan H, Chen W, Wang Y, Lin W, Zhong Z, Deng C
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114003
Journal of controlled release : official journal of the Controlled Release Society 2025 Sep 10;385:114003
Engineered biomimetic vesicles induce cuproptosis and disrupt efferocytosis for metastatic adenoid cystic carcinoma immunotherapy.
Li M, Dong W, Cui Y, Li J, Yang C, Zhang D, Fu X
Materials today. Bio 2025 Oct;34:102233
Materials today. Bio 2025 Oct;34:102233
Ultrasound-activated miR-195-5p/shikonin nanobubbles remodel immunosuppressive microenvironment via immunogenic cell death to potentiate PD-1/PD-L1 blockade in hepatocellular carcinoma.
Tan Y, Xu Q, Chen Y, Liu Y, Liu C, Cui X, Zhao Y
Materials today. Bio 2025 Oct;34:102216
Materials today. Bio 2025 Oct;34:102216
Light-controlled pyroptosis via redox-responsive microneedles enhances photodynamic-epigenetic immunotherapy in breast cancer.
Yu H, Chen Y, Yin J, Yuan Z, Feng S, Duan Y, Yan P, Liu S, Zhu W
Materials today. Bio 2025 Oct;34:102158
Materials today. Bio 2025 Oct;34:102158
Integrative multi-omics and machine learning identify CALR as a diagnostic and therapeutic target in aneurysmal subarachnoid hemorrhage.
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Experimental neurology 2025 Nov;393:115396
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Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.
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Microwave-Activated Bacterial Biorobot for Multimodal Cancer Therapy.
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e04603
Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy.
Tan H, Li N, Shu S, Fan Z, Deng J, Wu J, Zhou X, Huang Q, Cao X
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114242
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114242
Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment.
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Fundamental research 2025 May;5(3):1047-1062
Fundamental research 2025 May;5(3):1047-1062
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease.
Shen H, Xie Y, Wang Y, Xie Y, Wang Y, Su Z, Zhao L, Yao S, Cao X, Liang J, Long J, Zhong R, Tang J, Wang S, Zhang L, Wang X, Stork B, Cui L, Wu W
Autophagy 2025 May;21(5):1096-1115
Autophagy 2025 May;21(5):1096-1115
Metabolic reprogramming nanomedicine potentiates colon cancer sonodynamic immunotherapy by inhibiting the CD39/CD73/ADO pathway.
Zhang Y, Jin W, Deng Z, Gao B, Zhu Y, Fu J, Xu C, Wang W, Bai T, Jiao L, Wu H, Zhang M, Zhang M
Acta pharmaceutica Sinica. B 2025 May;15(5):2655-2672
Acta pharmaceutica Sinica. B 2025 May;15(5):2655-2672
Piezoelectric-Triggered Ferroptosis for Cancer Therapy via Cascade-Enhanced Immune Response.
Zheng H, Lin H, Ke Y, Ma Y, Ge S, Yang F, Ruan J, Jia R
Advanced healthcare materials 2025 May;14(14):e2501339
Advanced healthcare materials 2025 May;14(14):e2501339
Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury.
Qi J, Wang Y, Chen H, Wu K, Zhou P, Dou Y, Xiong B, Zhou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2407802
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2407802
Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine.
Huang J, Yang J, Yang Y, Lu X, Xu J, Lu S, Pan H, Zhou W, Li W, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(17):e2415227
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APOL6 as a potential biomarker of immuno-correlation and therapeutic prediction in cancer immunotherapy.
Yao J, Gan W, Sun J, Han Z, Li D, Cao L, Zhu L
Medicine 2025 May 9;104(19):e42406
Medicine 2025 May 9;104(19):e42406
An Implantable Double-Layered Spherical Scaffold Depositing Gene and Cell Agents to Facilitate Collaborative Cancer Immunotherapy.
Lei S, Gao Y, Wang K, Wu S, Zhu M, Chen X, Zhou W, Chen X, Zhang J, Duan X, Men K
ACS nano 2025 May 13;19(18):17653-17673
ACS nano 2025 May 13;19(18):17653-17673
Compromised efferocytosis during aging is related to COVID-19 severity in mice.
Ke X, Lin X, Wang J, Chen M, Jian X, Ye C, Chen Q
Virologica Sinica 2025 Jun;40(3):419-429
Virologica Sinica 2025 Jun;40(3):419-429
Biomimetic multifunctional nanoparticles for improved radiotherapy and immunotherapy in cancer treatment.
Chen J, Ran P, Xu Y, Khouchani M, Li X, Jian L, Abdelmajid T, Aittahssaint N, Yang Q, Li J, Zhao L
Materials today. Bio 2025 Jun;32:101698
Materials today. Bio 2025 Jun;32:101698
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
Wang C, Rong X, Zhang F, Mu X, Jiang J
Materials today. Bio 2025 Jun;32:101650
Materials today. Bio 2025 Jun;32:101650
A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma.
Fan Z, Pei Q, Sun H, Zhang H, Xie Z, Zhang T, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414592
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414592
Starting the Engine and Releasing the Brakes of T-Cell Responses: A Biomimetic Dendritic Cell Nanoplatform for Improved Glioblastoma Immunotherapy.
Kuang L, Han M, Wu X, Deng Z, Liu T, Yin Y, Tang Y, Dong Z, Hu X, Zhu S, Wang Z, Yin T, Wang Y
ACS nano 2025 Jun 17;19(23):21365-21384
ACS nano 2025 Jun 17;19(23):21365-21384
Hesperidin Derivatives Contained Hydrogel Dressing for Photothermal Treatment of Melanoma and Postoperative Tissue Regeneration.
He J, Zhou Z, Zhu W, Chen X, Zhu S, Sun J, Zuo Y, Yang M, Yu M, Yang L, Lei J, Shao W, He X, Liu H
ACS applied bio materials 2025 Jun 16;8(6):5321-5336
ACS applied bio materials 2025 Jun 16;8(6):5321-5336
EndoMAP.v1 charts the structural landscape of human early endosome complexes.
Gonzalez-Lozano MA, Schmid EW, Miguel Whelan E, Jiang Y, Paulo JA, Walter JC, Harper JW
Nature 2025 Jul;643(8070):252-261
Nature 2025 Jul;643(8070):252-261
Identification of a Novel Antibacterial Function of Mammalian Calreticulin.
Ma Y, Liu J, Qin X, Cui X, Yang Q
Biomolecules 2025 Jul 4;15(7)
Biomolecules 2025 Jul 4;15(7)
CALR promotes corneal epithelial cell proliferation and migration through Wnt7a.
Wang Q, Li Q, Wei N
Molecular biology reports 2025 Jul 16;52(1):714
Molecular biology reports 2025 Jul 16;52(1):714
Transformable albumin-based nanocapsules selectively amplify tumor starvation and disulfidptosis through metabolic deception.
Li Y, Lu Y, Lu W, Zhong N, Li N, Xu Z, Zhang J, Sun H, Wu F, Teng Z, Tang Y, Wang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113739
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor.
Yang W, Di S, Yang Z, Cao J, Fu Q, Ren H, Cheng H, Xie Y, Jia W, Dai X, Yu M, Chen Y, Cui X
Science advances 2025 Jan 31;11(5):eado7373
Science advances 2025 Jan 31;11(5):eado7373
EndoMAP.v1, a Structural Protein Complex Landscape of Human Endosomes.
Gonzalez-Lozano MA, Schmid EW, Whelan EM, Jiang Y, Paulo JA, Walter JC, Harper JW
bioRxiv : the preprint server for biology 2025 Feb 9;
bioRxiv : the preprint server for biology 2025 Feb 9;
Novel Indoleamine-2,3-Dioxygenase-Targeted Pt(IV) Prodrugs Regulate the Tumor Immune Microenvironment to Achieve Chemoimmunotherapy In Vitro and In Vivo.
Li Z, Liu XM, Tan F, Wang JQ, Qiao X, Feng YK, Xu JY, Hao JH
Journal of medicinal chemistry 2025 Feb 27;68(4):4352-4372
Journal of medicinal chemistry 2025 Feb 27;68(4):4352-4372
Sodium butyrate enhances sorafenib-induced ferroptosis and immunogenic cell death by modulating IRF2-Oasl2-cGAS pathway in colorectal cancer.
Xiang Y, Zheng J, Zhao X, Zhou L, Yan Q, Ma Y, Zhou Y, Jiang P, Fang Y, Li W, Pan Y, Tao H, Li W, Xiang F, Hua Y, Li Y, Zheng C, Ge W, Li Y, Yan S, Zhu Y, Xu G
Materials today. Bio 2025 Dec;35:102498
Materials today. Bio 2025 Dec;35:102498
Clinically friendly smart hydrogel boosts cuproptosis and PD-L1 upregulation to enhance anti-tumor immunotherapy.
Fu B, Li G, Yao Y, Zhang M, Zhong Y, Wang X, Chen Y, Liang W, Wang Y, Lin H, Zhang Y, Du Q, Xu Z, Cui H, Shi L, Chen X, Zhang J
Materials today. Bio 2025 Dec;35:102268
Materials today. Bio 2025 Dec;35:102268
Hypoxic migrasomes drive colorectal cancer liver metastasis by mediating CD5L(+) macrophage efferocytosis via NRP2/PROX1 axis.
Luo Y, Huang Y, Huang Y, Chen L
Journal of translational medicine 2025 Dec 8;23(1):1384
Journal of translational medicine 2025 Dec 8;23(1):1384
An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.
Liang XJ, Guo X, Zhu PH, Zhao ZH, You Z, Yang K, Song Y, Li L, Song XQ
Journal of medicinal chemistry 2025 Dec 25;68(24):26328-26347
Journal of medicinal chemistry 2025 Dec 25;68(24):26328-26347
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Li J, Zhang G, Sun Z, Jiang M, Jia G, Liu H, Liu N, Shi L, Zhang L, Nie L, Zhang Y, Fu Y
Biomaterials 2025 Aug;319:123201
Biomaterials 2025 Aug;319:123201
Harnessing prazosin for tumors: Liposome hybrid nanovesicles activate tumor immunotherapy via autophagy inhibition.
Xuanyuan X, Liu W, Jiang M, Zhang X, Wen B, Zheng R, Yao N, Zhang T, Feng Y, Qiao C, Zhang H, Luo D, Feng S, Li M, Gao J, Lu Z
Biomaterials 2025 Aug;319:123184
Biomaterials 2025 Aug;319:123184
Copper-Induced Cuproptosis and Immunogenic Cell Death Synergize with Radiotherapy and PD-1 Blockade in Osteosarcoma.
Yao J, Chen P, Xie D, Chen J, Lin X, Xu Y
ACS applied materials & interfaces 2025 Aug 20;17(33):46635-46650
ACS applied materials & interfaces 2025 Aug 20;17(33):46635-46650
Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.
Gupta T, Wu SR, Chang LC, Lin FC, Shan YS, Yeh CS, Su WP
Journal of nanobiotechnology 2025 Aug 12;23(1):562
Journal of nanobiotechnology 2025 Aug 12;23(1):562
Responsive plasmonic hybrid nanorods enables metabolism reprogramming via cuproptosis-photothermal combined cancer therapy.
Xie Q, Sun T, Zhang L, Gong M, Zhang W, Liu X, Zhao Y, Wang M, Yang X, Zhang Z, Liu G, Zhou C, Zhang D
Biomaterials 2025 Apr;315:122971
Biomaterials 2025 Apr;315:122971
Control Over Kinetic Self-Assembly of Phthalocyanine into Photothermal Nano-Vaccine Enabling Tunable Superlarge Absorption Redshift.
Zhang S, Li Y, Zheng J, Liu C, Diao C, Zhao L, Liu C
Advanced healthcare materials 2025 Apr;14(9):e2403494
Advanced healthcare materials 2025 Apr;14(9):e2403494
Enhanced cGAS-STING Activation and Immune Response by LPDAM Platform-Based Lapachone-Chemical-Photothermal Synergistic Therapy for Colorectal Cancer.
Pan X, Lin Y, Lin C, Liu S, Lin P, Lin X, He R, Ye Z, Ye J, Zhu G
Advanced healthcare materials 2025 Apr;14(11):e2403309
Advanced healthcare materials 2025 Apr;14(11):e2403309
Chimeric Antigen Receptor-Engineered Cell Membrane-Coated Nanoparticles Promote Dual-Targeted mRNA-Based Cancer Gene Therapy.
Lei S, Li J, Zhu M, Zhou W, Fu X, Wu S, Chen X, Zhang J, Duan X, Wang W, Men K
ACS nano 2025 Apr 29;19(16):15668-15684
ACS nano 2025 Apr 29;19(16):15668-15684
Tumor signal amplification and immune decoy strategy using bacterial membrane-coated nanoparticles for immunotherapy.
Li Y, Wang W, Xu J, Zhao B, Xiong L, Ge D, Wu Y, Dou X, Fu Y, Wang L, Zhao C, Chen M
Biomaterials science 2025 Apr 29;13(9):2368-2380
Biomaterials science 2025 Apr 29;13(9):2368-2380
Remodeling of Effector and Regulatory T Cells by Capture and Utilization of miRNAs Using Nanocomposite Hydrogel for Tumor-Specific Photothermal Immunotherapy.
Chen L, Zhu M, Zhang H, Tang W, Liu J, Tang X, Chang X, Zhu Z, Liu T, Weng L, Zhang Y, Chen X
ACS nano 2025 Apr 22;19(15):14873-14892
ACS nano 2025 Apr 22;19(15):14873-14892
Self-assembling chemodrug fiber-hydrogel for transarterial chemoembolization and radiotherapy-enhanced antitumor immunity.
Peng Y, Liu H, Liang X, Cao L, Teng M, Chen H, Li Z, Peng X, Mao J, Cheng H, Liu G
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:1-16
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:1-16
Nanoparticle/Engineered Bacteria Based Triple-Strategy Delivery System for Enhanced Hepatocellular Carcinoma Cancer Therapy.
Yang M, Chen W, Gupta D, Mei C, Yang Y, Zhao B, Qiu L, Chen J
International journal of nanomedicine 2024;19:3827-3846
International journal of nanomedicine 2024;19:3827-3846
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death.
Liang J, Tian X, Zhou M, Yan F, Fan J, Qin Y, Chen B, Huo X, Yu Z, Tian Y, Deng S, Peng Y, Wang Y, Liu B, Ma X
Biomaterials 2024 Sep;309:122608
Biomaterials 2024 Sep;309:122608
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Lu Y, Liang Z, Liu L, Zhou Y, Liu C, Zhao Z, Zheng T, Du Q, Liu W
European journal of medicinal chemistry 2024 Sep 5;275:116534
European journal of medicinal chemistry 2024 Sep 5;275:116534
Potentiated Calcium Carbonate with Enhanced Calcium Overload Induction and Acid Neutralization Capabilities to Boost Chemoimmunotherapy against Liver Cancer.
Zheng L, Ding Y, Fang S, Yang W, Chen J, Ma J, Wang M, Wang J, Zhang F, Guo X, Zhang K, Shu GF, Weng Q, Wu F, Zhao Z, Chen M, Jiansong J
ACS nano 2024 Oct 8;18(40):27597-27616
ACS nano 2024 Oct 8;18(40):27597-27616
Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy.
Huang H, Fu J, Peng H, He Y, Chang A, Zhang H, Hao Y, Xu X, Li S, Zhao J, Ni J, Dong X
Journal of nanobiotechnology 2024 Oct 21;22(1):647
Journal of nanobiotechnology 2024 Oct 21;22(1):647
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Hong J, Li X, Hao Y, Xu H, Yu L, Meng Z, Zhang J, Zhu M
Cell death and differentiation 2024 Nov;31(11):1561-1575
Cell death and differentiation 2024 Nov;31(11):1561-1575
Targeting delivery of mifepristone to endometrial dysfunctional macrophages for endometriosis therapy.
Zhang M, Ye Y, Chen Z, Wu X, Chen Y, Zhao P, Zhao M, Zheng C
Acta biomaterialia 2024 Nov;189:505-518
Acta biomaterialia 2024 Nov;189:505-518
Bimetallic peroxide nanoparticles induce PANoptosis by disrupting ion homeostasis for enhanced immunotherapy.
Hou G, Chen Y, Lei H, Lu Y, Liu L, Han Z, Sun S, Li J, Cheng L
Science advances 2024 Nov 8;10(45):eadp7160
Science advances 2024 Nov 8;10(45):eadp7160
Inhalable metal-organic framework-mediated cuproptosis combined with PD-L1 checkpoint blockade for lung metastasis synergistic immunotherapy.
Yan C, Liu Y, Zhao G, Yang H, Lv H, Li G, Li Y, Fu Y, Sun F, Feng Y, Li Y, Zhao Z
Acta pharmaceutica Sinica. B 2024 May;14(5):2281-2297
Acta pharmaceutica Sinica. B 2024 May;14(5):2281-2297
Enhancing cell pyroptosis with biomimetic nanoparticles for melanoma chemo-immunotherapy.
Sun S, He Y, Xu J, Leng S, Liu Y, Wan H, Yan L, Xu Y
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:470-485
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:470-485
A combination of PD-L1-targeted IL-15 mRNA nanotherapy and ultrasound-targeted microbubble destruction for tumor immunotherapy.
Wang X, Li F, Zhang J, Guo L, Shang M, Sun X, Xiao S, Shi D, Meng D, Zhao Y, Jiang C, Li J
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Mar;367:45-60
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Li X, Cheng Y, Yang Z, Ji Q, Huan M, Ye W, Liu M, Zhang B, Liu D, Zhou S
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Multiple Immunomodulatory Strategies Based on Targeted Regulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Immune Homeostasis against Hepatocellular Carcinoma.
Fang S, Zheng L, Shu GF, Xiaoxiao C, Guo X, Ding Y, Yang W, Chen J, Zhao Z, Tu J, Chen M, Ji JS
ACS nano 2024 Mar 26;18(12):8811-8826
ACS nano 2024 Mar 26;18(12):8811-8826
Cu(2)WS(4)-PEG Nanozyme as Multifunctional Sensitizers for Enhancing Immuno-Radiotherapy by Inducing Ferroptosis.
Fu S, Li Y, Shen L, Chen Y, Lu J, Ran Y, Zhao Y, Tang H, Tan L, Lin Q, Hao Y
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2309537
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2309537
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer.
Ye LY, Li YS, Ge T, Liu LC, Si JX, Yang X, Fan WJ, Liu XZ, Zhang YN, Wang JW, Wang SB, Zou H, Zheng YL, Jin KT, Mao ZW, Cai Y, Mou XZ
Advanced healthcare materials 2024 Jul;13(17):e2304136
Advanced healthcare materials 2024 Jul;13(17):e2304136
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy.
Li K, Wang J, Xie Y, Lu Z, Sun W, Wang K, Liang J, Chen X
Journal of nanobiotechnology 2024 Jul 8;22(1):400
Journal of nanobiotechnology 2024 Jul 8;22(1):400
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
Cheng S, Zhou T, Luo Y, Zhang J, Dong K, Zhang Q, Shu W, Zhang T, Zhang Q, Shi R, Yao Y, Wang H
Journal of nanobiotechnology 2024 Jul 11;22(1):408
Journal of nanobiotechnology 2024 Jul 11;22(1):408
Copper-coordinated nanoassemblies based on photosensitizer-chemo prodrugs and checkpoint inhibitors for enhanced apoptosis-cuproptosis and immunotherapy.
Liang W, Han C, Zhang D, Liu C, Zhu M, Xu F, Fang C, Zhang S, Liu C, Li Y
Acta biomaterialia 2024 Feb;175:341-352
Acta biomaterialia 2024 Feb;175:341-352
Engineered Microbial Nanohybrids for Tumor-Mediated NIR II Photothermal Enhanced Ferroptosis/Cuproptosis and Immunotherapy.
Ruan Y, Zhuang H, Zeng X, Lin L, Wang X, Xue P, Xu S, Chen Q, Yan S, Huang W
Advanced healthcare materials 2024 Feb;13(4):e2302537
Advanced healthcare materials 2024 Feb;13(4):e2302537
Thioredoxin domain containing 5 is involved in the hepatic storage of squalene into lipid droplets in a sex-specific way.
Sánchez-Marco J, Bidooki SH, Abuobeid R, Barranquero C, Herrero-Continente T, Arnal C, Martínez-Beamonte R, Lasheras R, Surra JC, Navarro MA, Rodríguez-Yoldi MJ, Arruebo M, Sebastian V, Osada J
The Journal of nutritional biochemistry 2024 Feb;124:109503
The Journal of nutritional biochemistry 2024 Feb;124:109503
Novel Carrier-Free Nanodrug Enhances Photodynamic Effects by Blocking the Autophagy Pathway and Synergistically Triggers Immunogenic Cell Death for the Efficient Treatment of Breast Cancer.
Xie L, Wang L, Li L, Liu C, Guo L, Liao Y, Zhou S, Wu W, Duo Y, Shi L, Yuan M
ACS applied materials & interfaces 2024 Feb 7;16(5):5683-5695
ACS applied materials & interfaces 2024 Feb 7;16(5):5683-5695
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy.
Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X, Chen X, Xie J, Ju S
Nature communications 2024 Feb 6;15(1):1118
Nature communications 2024 Feb 6;15(1):1118
Proton-Gradient-Driven Porphyrin-Based Liposome Remote-Loaded with Imiquimod as In Situ Nanoadjuvants for Synergistically Augmented Tumor Photoimmunotherapy.
Liu D, Fu L, Gong L, Li S, Li K, Liu K, Yang D
ACS applied materials & interfaces 2024 Feb 21;16(7):8403-8416
ACS applied materials & interfaces 2024 Feb 21;16(7):8403-8416
Engineered low-pathogenic Helicobacter pylori as orally tumor immunomodulators for the stimulation of systemic immune response.
Zeng Z, Sun Y, Jiang J, Xu X, Lin H, Li W, Zheng D, Huang Y, Zhao C
Biomaterials 2024 Dec;311:122672
Biomaterials 2024 Dec;311:122672
Inhalable nanoparticles with enhanced cuproptosis and cGAS-STING activation for synergistic lung metastasis immunotherapy.
Yan C, Lv H, Feng Y, Li Y, Zhao Z
Acta pharmaceutica Sinica. B 2024 Aug;14(8):3697-3710
Acta pharmaceutica Sinica. B 2024 Aug;14(8):3697-3710
Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment.
Zheng M, Wang Y, Fu F, Zhang K, Wang Y, Zhao S, Liu Q, Mu H, Zhang X, Miao L
International journal of biological sciences 2023;19(13):4278-4290
International journal of biological sciences 2023;19(13):4278-4290
Multifunctional Nanoplatform-Mediated Chemo-Photothermal Therapy Combines Immunogenic Cell Death with Checkpoint Blockade to Combat Triple-Negative Breast Cancer and Distant Metastasis.
Zhu H, Yang K, Yao H, Chen X, Yan S, He Y, Cao Y, Luo J, Wang D
International journal of nanomedicine 2023;18:3109-3124
International journal of nanomedicine 2023;18:3109-3124
Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles.
Lu M, Xing H, Shao W, Wu P, Fan Y, He H, Barth S, Zheng A, Liang XJ, Huang Y
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3945-3955
Acta pharmaceutica Sinica. B 2023 Sep;13(9):3945-3955
Neuroprotective role of calreticulin after spinal cord injury in mice.
Melnikova A, Ishii H, Tamatani T, Hattori T, Takarada-Iemata M, Hori O
Neuroscience research 2023 Oct;195:29-36
Neuroscience research 2023 Oct;195:29-36
Combination of ferroptosis and pyroptosis dual induction by triptolide nano-MOFs for immunotherapy of Melanoma.
Wang S, Guo Q, Xu R, Lin P, Deng G, Xia X
Journal of nanobiotechnology 2023 Oct 19;21(1):383
Journal of nanobiotechnology 2023 Oct 19;21(1):383
Cell type-specific translational regulation by human DUS enzymes.
Yu NJ, Dai W, Li A, He M, Kleiner RE
bioRxiv : the preprint server for biology 2023 Nov 8;
bioRxiv : the preprint server for biology 2023 Nov 8;
Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma.
Xu T, Zhu C, Song F, Zhang W, Yuan M, Pan Z, Huang P
BMC cancer 2023 Nov 21;23(1):1131
BMC cancer 2023 Nov 21;23(1):1131
Combinatorial selective ER-phagy remodels the ER during neurogenesis.
Hoyer MJ, Capitanio C, Smith IR, Paoli JC, Bieber A, Jiang Y, Paulo JA, Gonzalez-Lozano MA, Baumeister W, Wilfling F, Schulman BA, Harper JW
bioRxiv : the preprint server for biology 2023 Nov 10;
bioRxiv : the preprint server for biology 2023 Nov 10;
Pre-Induced ICD Membrane-Coated Carrier-Free Nanoparticles for the Personalized Lung Cancer Immunotherapy.
Li S, Jiang S, Rahman MSU, Mei J, Wang X, Jiang J, Chen Y, Xu S, Liu Y
Small methods 2023 May;7(5):e2201569
Small methods 2023 May;7(5):e2201569
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
Li J, Hui Y, Xu Z, Tan J, Yin K, Kuang L, Tang Y, Wei J, Zhong Q, Zheng T
iScience 2023 Mar 17;26(3):106271
iScience 2023 Mar 17;26(3):106271
Engineered bacteria combined with doxorubicin nanoparticles suppress angiogenesis and metastasis in murine melanoma models.
Yang M, Conceição M, Chen W, Yang F, Zhao B, Wood MJA, Qiu L, Chen J
Acta biomaterialia 2023 Mar 1;158:734-746
Acta biomaterialia 2023 Mar 1;158:734-746
Downregulation of Calreticulin and Annexin A2 Expression in Acquired Middle Ear Cholesteatoma by 2-DE Analysis.
Chang NC, Wu YJ, Wang LF, Chan LP, Chai CY, Chen Ms WT, Tsai SM, Chien CY, Ho KY
The Annals of otology, rhinology, and laryngology 2023 Jun;132(6):684-691
The Annals of otology, rhinology, and laryngology 2023 Jun;132(6):684-691
NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.
Xu Z, Lu Q, Shan M, Jiang G, Liu Y, Yang Z, Lu Y, Liu W
Journal of medicinal chemistry 2023 Jun 22;66(12):7813-7833
Journal of medicinal chemistry 2023 Jun 22;66(12):7813-7833
ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions.
Tanaka T, Nguyen DT, Kwankaew N, Sumizono M, Shinoda R, Ishii H, Takarada-Iemata M, Hattori T, Oyadomari S, Kato N, Mori K, Hori O
Neurochemical research 2023 Jul;48(7):2175-2186
Neurochemical research 2023 Jul;48(7):2175-2186
Rhythm Mild-Temperature Photothermal Therapy Enhancing Immunogenic Cell Death Response in Oral Squamous Cell Carcinoma.
Ran J, Liu T, Song C, Wei Z, Tang C, Cao Z, Zou H, Zhang X, Cai Y, Han W
Advanced healthcare materials 2023 Jan;12(6):e2202360
Advanced healthcare materials 2023 Jan;12(6):e2202360
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Jiang X, Liu K, Jiang H, Yin H, Wang ED, Cheng H, Yuan F, Xiao F, Wang F, Lu W, Peng B, Shu Y, Li X, Chen S, Guo F
Cell reports 2023 Jan 31;42(1):111984
Cell reports 2023 Jan 31;42(1):111984
SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR.
Cui S, Hu H, Chen A, Cui M, Pan X, Zhang P, Wang G, Wang H, Hao H
Acta pharmaceutica Sinica. B 2023 Feb;13(2):559-576
Acta pharmaceutica Sinica. B 2023 Feb;13(2):559-576
Biomimetic Prussian blue nanocomplexes for chemo-photothermal treatment of triple-negative breast cancer by enhancing ICD.
Long Y, Fan J, Zhou N, Liang J, Xiao C, Tong C, Wang W, Liu B
Biomaterials 2023 Dec;303:122369
Biomaterials 2023 Dec;303:122369
Nanointegrative In Situ Reprogramming of Tumor-Intrinsic Lipid Droplet Biogenesis for Low-Dose Radiation-Activated Ferroptosis Immunotherapy.
Zhang Q, Wang X, Zhao Y, Cheng Z, Fang D, Liu Y, Tian G, Li M, Luo Z
ACS nano 2023 Dec 26;17(24):25419-25438
ACS nano 2023 Dec 26;17(24):25419-25438
Improving nanochemoimmunotherapy efficacy by boosting "eat-me" signaling and downregulating "don't-eat-me" signaling with Ganoderma lucidum polysaccharide-based drug delivery.
Pang G, Wei S, Zhao J, Wang FJ
Journal of materials chemistry. B 2023 Dec 13;11(48):11562-11577
Journal of materials chemistry. B 2023 Dec 13;11(48):11562-11577
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block "eat-me" signal.
Luo M, Wang X, Wu S, Yang C, Su Q, Huang L, Fu K, An S, Xie F, To KKW, Wang F, Fu L
Signal transduction and targeted therapy 2023 Aug 23;8(1):312
Signal transduction and targeted therapy 2023 Aug 23;8(1):312
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Wen H, Zhong Y, Yin Y, Qin K, Yang L, Li D, Yu W, Yang C, Deng Z, Hong K
International journal of biological sciences 2022;18(7):2898-2913
International journal of biological sciences 2022;18(7):2898-2913
Targeted Nanobubbles of PD-L1 mAb Combined with Doxorubicin as a Synergistic Tumor Repressor in Hepatocarcinoma.
Chen Y, Luo X, Liu Y, Zou Y, Yang S, Liu C, Zhao Y
International journal of nanomedicine 2022;17:3989-4008
International journal of nanomedicine 2022;17:3989-4008
Antigen Presentation Machinery Signature-Derived CALR Mediates Migration, Polarization of Macrophages in Glioma and Predicts Immunotherapy Response.
Chen R, Zhang H, Wu W, Li S, Wang Z, Dai Z, Liu Z, Zhang J, Luo P, Xia Z, Cheng Q
Frontiers in immunology 2022;13:833792
Frontiers in immunology 2022;13:833792
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Wang X, Liu Y, Xue C, Hu Y, Zhao Y, Cai K, Li M, Luo Z
Nature communications 2022 Sep 28;13(1):5685
Nature communications 2022 Sep 28;13(1):5685
Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy.
Shi M, Zhang J, Wang Y, Han Y, Zhao X, Hu H, Qiao M, Chen D
Acta biomaterialia 2022 Sep 15;150:353-366
Acta biomaterialia 2022 Sep 15;150:353-366
Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication.
Song W, Yang F, Yang H, Xu Y, Song SJ, Meng Y, Wei ST, Wan T, Zhou Y, Zhou B, Kuang J, Yu T, Qiu WX
Journal of medicinal chemistry 2022 Nov 10;65(21):14832-14842
Journal of medicinal chemistry 2022 Nov 10;65(21):14832-14842
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Chen J, Liu Y, Pan D, Xu T, Luo Y, Wu W, Wu P, Zhu H, Li D
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
ER-Targeting PDT Converts Tumors into In Situ Therapeutic Tumor Vaccines.
Liu X, Liu Y, Li X, Huang J, Guo X, Zhang J, Luo Z, Shi Y, Jiang M, Qin B, Du Y, Luo L, You J
ACS nano 2022 Jun 28;16(6):9240-9253
ACS nano 2022 Jun 28;16(6):9240-9253
Combination of oxaliplatin and POM-1 by nanoliposomes to reprogram the tumor immune microenvironment.
Fu X, Shi Y, Zang H, Wang Q, Wang Y, Wu H, Qiu S, Shen H, Mo F, Zhang Y, Lin G
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:1-13
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:1-13
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Membrane protective role of autophagic machinery during infection of epithelial cells by Candida albicans.
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Gut microbes 2022 Jan-Dec;14(1):2004798
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European journal of medicinal chemistry 2022 Dec 15;244:114830
European journal of medicinal chemistry 2022 Dec 15;244:114830
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Redox biology 2022 Aug;54:102351
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ACS applied materials & interfaces 2022 Apr 13;14(14):15894-15910
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miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
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BioMed research international 2021;2021:6650181
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Journal of nanobiotechnology 2021 Sep 30;19(1):297
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Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
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Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
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Calreticulin as a special marker to distinguish dental pulp stem cells from gingival mesenchymal stem cells.
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International journal of biological macromolecules 2021 May 1;178:229-239
International journal of biological macromolecules 2021 May 1;178:229-239
The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.
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Scientific reports 2021 Jun 22;11(1):13086
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Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.
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Aging 2021 Feb 11;13(4):5607-5620
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Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum.
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Toxicology 2021 Apr 15;453:152736
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Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
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Nature metabolism 2020 Mar;2(3):256-269
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Naphthyl quinoxaline thymidine conjugate is a potent anticancer agent post UVA activation and elicits marked inhibition of tumor growth through vaccination.
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European journal of medicinal chemistry 2019 Jun 1;171:255-264
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BMC ophthalmology 2019 Aug 2;19(1):168
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Diabetologia 2018 May;61(5):1124-1134
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Scientific reports 2018 Jul 2;8(1):9972
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The international journal of biochemistry & cell biology 2017 Sep;90:103-113
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International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
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Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
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A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
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Diagnostic pathology 2013 Apr 15;8:58
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Deisenroth C, Itahana Y, Tollini L, Jin A, Zhang Y
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
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Proteome science 2011 Apr 8;9:17
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Journal of proteome research 2010 Mar 5;9(3):1402-15
Journal of proteome research 2010 Mar 5;9(3):1402-15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 10292-1-AP(calreticulin antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 10292-1-AP(calreticulin antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The calreticulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human calreticulin. This antibody recognizes human,mouse,rat antigen. The calreticulin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
