Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DCABH-139 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DCABH-139, RRID:AB_2474209
- Product name
- Rabbit Anti-CALR monoclonal antibody, clone TV48-14
- Antibody type
- Monoclonal
- Description
- Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- TV48-14
- Vial size
- 100 _l
- Storage
- Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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