BS7973

antibody from Bioworld Technology, Inc

Targeting: TADA3 ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7973

Provider

Bioworld Technology, Inc

Product name

TADA3L polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human TADA3L.

Description

ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L. ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex is the human homolog of the yeast SAGA complex. ADA3 interacts with the E6 gene and is a target of E6-induced degradation. ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants. ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.