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- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- HPA005464 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA005464, RRID:AB_1848965
- Product name
- Anti-FMNL2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FMNL2, Gene description: formin-like 2, Alternative Gene Names: FHOD2, KIAA1902, Validated applications: ICC, IHC, WB, Uniprot ID: Q96PY5, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references IntAct: A nondisruptive internal tagging strategy to study the organization and function of actin isoforms
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
A Rac1-FMNL2 signaling module affects cell-cell contact formation independent of Cdc42 and membrane protrusions
Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1
Characterization of Diaphanous-related formin FMNL2 in human tissues
Parent C, van Zwam M, Dhar A, Bosman W, van Straaten W, Weijers S, Seta E, Joosten B, van Haren J, Palani S, van den Dries K
PLOS Biology 2024;22(3):e3002551
PLOS Biology 2024;22(3):e3002551
Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
Fung T, Chakrabarti R, Kollasser J, Rottner K, Stradal T, Kage F, Higgs H
Current Biology 2022;32(7):1577-1592.e8
Current Biology 2022;32(7):1577-1592.e8
A Rac1-FMNL2 signaling module affects cell-cell contact formation independent of Cdc42 and membrane protrusions
Komarova Y, Grobe H, Wüstenhagen A, Baarlink C, Grosse R, Grikscheit K
PLOS ONE 2018;13(3):e0194716
PLOS ONE 2018;13(3):e0194716
Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1
Grikscheit K, Frank T, Wang Y, Grosse R
Journal of Cell Biology 2015;209(3):367-376
Journal of Cell Biology 2015;209(3):367-376
Characterization of Diaphanous-related formin FMNL2 in human tissues
Gardberg M, Talvinen K, Kaipio K, Iljin K, Kampf C, Uhlen M, Carpén O
BMC Cell Biology 2010;11(1)
BMC Cell Biology 2010;11(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and liver tissues using HPA005464 antibody. Corresponding FMNL2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
