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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA019035 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA019035, RRID:AB_1844429
- Product name
- Anti-ABCB11
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ABCB11, Gene description: ATP-binding cassette, sub-family B (MDR/TAP), member 11, Alternative Gene Names: ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP, Validated applications: IHC, Uniprot ID: O95342, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.5 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy
Co-existence of ABCB11 and DCDC2 disease: Infantile cholestasis requires both next-generation sequencing and clinical-histopathologic correlation
Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet
Mutations in TJP2 cause progressive cholestatic liver disease
Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma
Mayer C, Nehring S, Kücken M, Repnik U, Seifert S, Sljukic A, Delpierre J, Morales‐Navarrete H, Hinz S, Brosch M, Chung B, Karlsen T, Huch M, Kalaidzidis Y, Brusch L, Hampe J, Schafmayer C, Zerial M
EMBO reports 2023;24(9)
EMBO reports 2023;24(9)
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy
Karolczak S, Deshwar A, Aristegui E, Kamath B, Lawlor M, Andreoletti G, Volpatti J, Ellis J, Yin C, Dowling J
Journal of Clinical Investigation 2023;133(18)
Journal of Clinical Investigation 2023;133(18)
Co-existence of ABCB11 and DCDC2 disease: Infantile cholestasis requires both next-generation sequencing and clinical-histopathologic correlation
Vogel G, Maurer E, Entenmann A, Straub S, Knisely A, Janecke A, Müller T
European Journal of Human Genetics 2020;28(6):840-844
European Journal of Human Genetics 2020;28(6):840-844
Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet
Kanda T, Okushin K, Tsutsumi T, Ikeuchi K, Kado A, Enooku K, Fujinaga H, Yamauchi N, Ushiku T, Moriya K, Yotsuyanagi H, Koike K
PLOS ONE 2020;15(8):e0234750
PLOS ONE 2020;15(8):e0234750
Mutations in TJP2 cause progressive cholestatic liver disease
Sambrotta M, Strautnieks S, Papouli E, Rushton P, Clark B, Parry D, Logan C, Newbury L, Kamath B, Ling S, Grammatikopoulos T, Wagner B, Magee J, Sokol R, Mieli-Vergani G, Smith J, Johnson C, McClean P, Simpson M, Knisely A, Bull L, Thompson R
Nature Genetics 2014;46(4):326-328
Nature Genetics 2014;46(4):326-328
Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma
Blackmore L, Knisely A, Hartley J, McKay K, Gissen P, Marcus R, Shawcross D
Journal of Clinical and Experimental Hepatology 2013;3(2):159-161
Journal of Clinical and Experimental Hepatology 2013;3(2):159-161
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skeletal muscle tissues using HPA019035 antibody. Corresponding ABCB11 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
