H00171023-M05

antibody from Novus Biologicals

Targeting: ASXL1 KIAA0978

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

H00171023-M05

Provider

Novus Biologicals

Proper citation

Novus Cat#H00171023-M05, RRID:AB_11038651

Product name

Mouse Monoclonal ASXL1 Antibody

Antibody type

Monoclonal

Description

IgG purified.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

0.1 mg

Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

References

Submitted references

ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts.

Valletta S, Dolatshad H, Bartenstein M, Yip BH, Bello E, Gordon S, Yu Y, Shaw J, Roy S, Scifo L, Schuh A, Pellagatti A, Fulga TA, Verma A, Boultwood J
Oncotarget 2015 Dec 29;6(42):44061-71

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Germline mutations in BAP1 impair its function in DNA double-strand break repair.

Ismail IH, Davidson R, Gagné JP, Xu ZZ, Poirier GG, Hendzel MJ
Cancer research 2014 Aug 15;74(16):4282-94

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Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34⁺ progenitor cells.

Davies C, Yip BH, Fernandez-Mercado M, Woll PS, Agirre X, Prosper F, Jacobsen SE, Wainscoat JS, Pellagatti A, Boultwood J
British journal of haematology 2013 Mar;160(6):842-50

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: ASXL1 Antibody (6E2) [H00171023-M05] - Analysis of ASXL1 expression in MCF-7 (Cat # L046V1).

ELISA

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

ELISA: ASXL1 Antibody (6E2) [H00171023-M05] - Detection limit for recombinant GST tagged ASXL1 is 0.3 ng/ml as a capture antibody.