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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- GTX127284 - Provider product page
- Provider
- GeneTex
- Product name
- ASXL1 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Asxl1 ablation in mouse embryonic stem cells impairs neural differentiation without affecting self-renewal.
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.
Role of Asxl1 in kidney podocyte development via its interaction with Wtip.
An S, Park UH, Moon S, Kang M, Youn H, Hwang JT, Kim EJ, Um SJ
Biochemical and biophysical research communications 2019 Jan 15;508(3):907-913
Biochemical and biophysical research communications 2019 Jan 15;508(3):907-913
Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ
Cell death & disease 2018 Nov 2;9(11):1118
Cell death & disease 2018 Nov 2;9(11):1118
Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.
Youn HS, Kim TY, Park UH, Moon ST, An SJ, Lee YK, Hwang JT, Kim EJ, Um SJ
Scientific reports 2017 Jul 12;7(1):5198
Scientific reports 2017 Jul 12;7(1):5198
Role of Asxl1 in kidney podocyte development via its interaction with Wtip.
Moon S, Um SJ, Kim EJ
Biochemical and biophysical research communications 2015 Oct 23;466(3):560-6
Biochemical and biophysical research communications 2015 Oct 23;466(3):560-6
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- ASXL1 antibody detects ASXL1 protein by western blot analysis.A. 50 ?g 293T whole cell lysate/extractB. 50 ?g whole cell lysate/extract of GFP-human ASXL1-transfected 293T cellsASXL1 antibody (GTX127284) dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- ASXL1 antibody detects ASXL1 protein at nucleus in human esophagus carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human esophagus carcinoma. ASXL1 antibody (GTX127284) diluted at 1:500.
