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- Antibody Data
- Antigen structure
- References [4]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN950543 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Additional Sex Combs Like 1 (Drosophila) (ASXL1) (AA 521-549) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography on Protein A
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 521-549
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The most commonly reported variant in ASXL1 (c.1934dupG;p.Gly646TrpfsX12) is not a somatic alteration.
High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression.
Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations.
Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations.
Abdel-Wahab O, Kilpivaara O, Patel J, Busque L, Levine RL
Leukemia 2010 Sep;24(9):1656-7
Leukemia 2010 Sep;24(9):1656-7
High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression.
Boultwood J, Perry J, Zaman R, Fernandez-Santamaria C, Littlewood T, Kusec R, Pellagatti A, Wang L, Clark RE, Wainscoat JS
Leukemia 2010 Jun;24(6):1139-45
Leukemia 2010 Jun;24(6):1139-45
Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations.
Sugimoto Y, Muramatsu H, Makishima H, Prince C, Jankowska AM, Yoshida N, Xu Y, Nishio N, Hama A, Yagasaki H, Takahashi Y, Kato K, Manabe A, Kojima S, Maciejewski JP
British journal of haematology 2010 Jul;150(1):83-7
British journal of haematology 2010 Jul;150(1):83-7
Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations.
Szpurka H, Jankowska AM, Makishima H, Bodo J, Bejanyan N, Hsi ED, Sekeres MA, Maciejewski JP
Leukemia research 2010 Aug;34(8):969-73
Leukemia research 2010 Aug;34(8):969-73
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of ASXL1 Antibody (Center) Cat.-No AP50279PU-N with Hela cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
