Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8130 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TSPAN32 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human TSPAN32.
- Description
- Phemx (pan-hematopoietic expression protein), also known as PHMX, TSPAN32 (tetraspanin-32) or TSSC6 (tumor-suppressing subtransferable candidate 6), is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin Ï«IIb/Integrin ÉÇ3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate ¡ùoutside-in¡ì signaling. This interaction may be important in the process of wound healing.The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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