Explore
Validate
LearnAP21691SU-S
antibody from Acris Antibodies GmbH
Targeting: BIRC2
API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AP21691SU-S - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AP21691SU-S, RRID:AB_10758449
- Product name
- anti IAP2 / BIRC2
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to amino acids 2-18 (HKTASQRLFPGPSYQNI) of human cIAP1
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 50 µl
Submitted references Expression and localization of inhibitor of apoptosis proteins in normal human tissues.
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.
The inhibitors of apoptosis: there is more to life than Bcl2.
Vischioni B, van der Valk P, Span SW, Kruyt FA, Rodriguez JA, Giaccone G
Human pathology 2006 Jan;37(1):78-86
Human pathology 2006 Jan;37(1):78-86
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.
Wright CW, Duckett CS
The Journal of clinical investigation 2005 Oct;115(10):2673-8
The Journal of clinical investigation 2005 Oct;115(10):2673-8
The inhibitors of apoptosis: there is more to life than Bcl2.
Liston P, Fong WG, Korneluk RG
Oncogene 2003 Nov 24;22(53):8568-80
Oncogene 2003 Nov 24;22(53):8568-80
No comments: Submit comment
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immuhistochemical analysis of a formalin-fixed, paraffin-embedded human ovarian cancer tissue microarray using AP21691SU-S at 1/2000. Differential expression of cIAP1 is seen between patient samples. Hematoxylin-eosin counterstain.
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immuhistochemical analysis of formalin-fixed, paraffin-embedded human breast tissue using AP21691SU-S at 1/2000. A, normal breast tissue. B, ductal carcinoma in situ (DCIS). C, invasive breast carcinoma. A1, B1, and C1 are higher magnifications of A, B and C, respectively. Hematoxylin-eosin counterstain. Increased cIAP1 expression is seen in the cancerous compared to normal breast tissue. Hematoxylin-eosin counterstain.
