NB100-56130
antibody from Novus Biologicals
Targeting: BIRC2
API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB100-56130 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56130, RRID:AB_838029
- Product name
- Rabbit Polyclonal cIAP-1/HIAP-2 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. cIAP1 has 618 amino acids and migrates at ~70 kDa on SDS-PAGE. Observed molecular weights may vary as genes generally produce, by alternative splicing, multiple transcripts all with introns, putatively encoding multiple different protein isoforms. Additionally, proteins may undergo post translational modifications including phosphorylation, glycosylation and cleavage which can result in differential molecular weights. Protein modifications can vary between cell and tissue type, and proteins can migrate as one or multiple bands depending on the isoform expressed as well as post-translational modifications.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: cIAP-1/HIAP-2 Antibody - Unpurified [NB100-56130] - cIAP-1/HIAP-2 Antibody [NB100-56130] - Analysis of formalin-fixed, paraffin-embedded human breast tissue using this antibody at 1:2000. A, normal breast tissue. B, ductal carcinoma in situ (DCIS). C, invasive breast carcinoma. A1, B1, and C1 are higher magnifications of A, B and C, respectively. Hematoxylin-eosin counterstain. Increased cIAP1 expression is seen in the cancerous compared to normal breast tissue. Hematoxylin-eosin counterstain.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: cIAP-1/HIAP-2 Antibody - Unpurified [NB100-56130] - cIAP-1/HIAP-2 Antibody [NB100-56130] - Analysis of a formalin-fixed, paraffin-embedded human ovarian cancer tissue microarray using this antibody at 1:2000. Differential expression of cIAP-1/HIAP-2 is seen between patient samples. Hematoxylin-eosin counterstain.