Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- 21100-1 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IFN-alpha Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Neutralizes human interferon alpha
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 ug
- Storage
- After receipt, the product may be stored at -20degreesC for short-term use ( = 6 months). For long-term storage, we recommend storing the product at -70degreesC or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Re-freezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Submitted references Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.
Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors.
Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus.
Neutralizing type I IFN antibodies trigger an IFN-like response in endothelial cells.
Neutralizing type I IFN antibodies trigger an IFN-like response in endothelial cells.
Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells.
Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I
PLoS pathogens 2017 May;13(5):e1006387
PLoS pathogens 2017 May;13(5):e1006387
Constitutively Active MAVS Inhibits HIV-1 Replication via Type I Interferon Secretion and Induction of HIV-1 Restriction Factors.
Gupta S, Termini JM, Issac B, Guirado E, Stone GW
PloS one 2016;11(2):e0148929
PloS one 2016;11(2):e0148929
Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus.
Zahn S, Rehkämper C, Kümmerer BM, Ferring-Schmidt S, Bieber T, Tüting T, Wenzel J
The Journal of investigative dermatology 2011 Jan;131(1):133-40
The Journal of investigative dermatology 2011 Jan;131(1):133-40
Neutralizing type I IFN antibodies trigger an IFN-like response in endothelial cells.
Moll HP, Freudenthaler H, Zommer A, Buchberger E, Brostjan C
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 15;180(8):5250-6
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 15;180(8):5250-6
Neutralizing type I IFN antibodies trigger an IFN-like response in endothelial cells.
Moll HP, Freudenthaler H, Zommer A, Buchberger E, Brostjan C
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 15;180(8):5250-6
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 15;180(8):5250-6
Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells.
Megjugorac NJ, Young HA, Amrute SB, Olshalsky SL, Fitzgerald-Bocarsly P
Journal of leukocyte biology 2004 Mar;75(3):504-14
Journal of leukocyte biology 2004 Mar;75(3):504-14
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