Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13637-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13637-1-AP, RRID:AB_2211547
- Product name
- TULP3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TULP3 antibody (Cat. #13637-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Distribution of ciliary adaptor proteins tubby and TULP3 in the organ of Corti.
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.
Multiple ciliary localization signals control INPP5E ciliary targeting.
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
Comparison of Ciliary Targeting of Two Rhodopsin-Like GPCRs: Role of C-Terminal Localization Sequences in Relation to Cilium Type.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.
Deletion of the phosphatase INPP5E in the murine retina impairs photoreceptor axoneme formation and prevents disc morphogenesis.
MicroRNA-506 has a suppressive effect on the tumorigenesis of nonsmall-cell lung cancer by regulating tubby-like protein 3.
Differential Roles of Tubby Family Proteins in Ciliary Formation and Trafficking.
RABL2 positively controls localization of GPCRs in mammalian primary cilia.
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
Lindner LA, Derstroff D, Oliver D, Reimann K
Frontiers in neuroscience 2023;17:1162937
Frontiers in neuroscience 2023;17:1162937
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.
Elliott KH, Balchand SK, Bonatto Paese CL, Chang CF, Yang Y, Brown KM, Rasicci DT, He H, Thorner K, Chaturvedi P, Murray SA, Chen J, Porollo A, Peterson KA, Brugmann SA
Development (Cambridge, England) 2023 Apr 15;150(8)
Development (Cambridge, England) 2023 Apr 15;150(8)
Multiple ciliary localization signals control INPP5E ciliary targeting.
Cilleros-Rodriguez D, Martin-Morales R, Barbeito P, Deb Roy A, Loukil A, Sierra-Rodero B, Herranz G, Pampliega O, Redrejo-Rodriguez M, Goetz SC, Izquierdo M, Inoue T, Garcia-Gonzalo FR
eLife 2022 Sep 5;11
eLife 2022 Sep 5;11
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
Schembs L, Willems A, Hasenpusch-Theil K, Cooper JD, Whiting K, Burr K, Bøstrand SMK, Selvaraj BT, Chandran S, Theil T
Cell reports 2022 May 17;39(7):110811
Cell reports 2022 May 17;39(7):110811
Comparison of Ciliary Targeting of Two Rhodopsin-Like GPCRs: Role of C-Terminal Localization Sequences in Relation to Cilium Type.
Chadha A, Paniagua AE, Williams DS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Sep 8;41(36):7514-7531
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Sep 8;41(36):7514-7531
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K
Biology open 2021 Sep 15;10(9)
Biology open 2021 Sep 15;10(9)
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.
Chen C, Xu Q, Zhang Y, Davies BA, Huang Y, Katzmann DJ, Harris PC, Hu J, Ling K
Science advances 2021 Jun;7(26)
Science advances 2021 Jun;7(26)
Deletion of the phosphatase INPP5E in the murine retina impairs photoreceptor axoneme formation and prevents disc morphogenesis.
Sharif AS, Gerstner CD, Cady MA, Arshavsky VY, Mitchell C, Ying G, Frederick JM, Baehr W
The Journal of biological chemistry 2021 Jan-Jun;296:100529
The Journal of biological chemistry 2021 Jan-Jun;296:100529
MicroRNA-506 has a suppressive effect on the tumorigenesis of nonsmall-cell lung cancer by regulating tubby-like protein 3.
Li ZH, Zhou JH, Chen SN, Pan L, Feng Y, Luo MQ, Li RX, Sun GL
Bioengineered 2021 Dec;12(2):10176-10186
Bioengineered 2021 Dec;12(2):10176-10186
Differential Roles of Tubby Family Proteins in Ciliary Formation and Trafficking.
Hong JJ, Kim KE, Park SY, Bok J, Seo JT, Moon SJ
Molecules and cells 2021 Aug 31;44(8):591-601
Molecules and cells 2021 Aug 31;44(8):591-601
RABL2 positively controls localization of GPCRs in mammalian primary cilia.
Dateyama I, Sugihara Y, Chiba S, Ota R, Nakagawa R, Kobayashi T, Itoh H
Journal of cell science 2019 Jan 16;132(2)
Journal of cell science 2019 Jan 16;132(2)
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
Hong CJ, Hamilton BA
PLoS genetics 2016 Oct;12(10):e1006357
PLoS genetics 2016 Oct;12(10):e1006357
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 13637-1-AP(TULP3 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TULP3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TULP3. This antibody recognizes human, mouse, rat antigen. The TULP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.