Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-3041 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-TLR1 Antibody
- Antibody type
- Polyclonal
- Description
- Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Antigen sequence
A partial length recombinant TLR1 p
rotein (amino acids 300-500) was us
ed as the immunogen for this antibo
dy.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of TLR1. Anti- TLR1 antibody (11-3041) was used at 4 µg/ml on (1) Jurkat, (2) EL4 and (3) Raji lysates.