334502

TLR1 antibody from BioLegend
CD281, KIAA0012, rsc786
Immunocytochemistry
Recommended by provider
Immunoprecipitation
Recommended by provider
Flow cytometry
Supportive data in Antibodypedia

Antibody data

Product number
334502
Provider
BioLegend
Proper citation
BioLegend Cat#334502, RRID:AB_1186023
Product name
Purified anti-human CD281 (TLR1)
Provider product page
BioLegend - 334502
Antibody type
Monoclonal
Antigen
Human TLR1 transfected Ba/F3
Description
Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been indentified. Toll-like receptor 1 (TLR1), known as CD281, is expressed on monocytes/macrophages, dendritic cells, and granulocytes and some lymphocytes at low levels. By association with TLR2, TLR1 is a coreceptor involved in the response to diverse set of pathogens, such as triacylated lipopeptidess (but not diacylated lipopeptides), peptidoglycans, lipoteichoic acid.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
Provider Type Product Number
- No reagents -