Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3541 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3541, RRID:AB_1581367
- Product name
- Tlr1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of Tlr1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Hajjar AM, O'Mahony DS, Ozinsky A, Underhill DM, Aderem A, Klebanoff SJ, Wilson CB
Journal of immunology (Baltimore, Md. : 1950) 2001 Jan 1;166(1):15-9
Journal of immunology (Baltimore, Md. : 1950) 2001 Jan 1;166(1):15-9
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.
Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A
Proceedings of the National Academy of Sciences of the United States of America 2000 Dec 5;97(25):13766-71
Proceedings of the National Academy of Sciences of the United States of America 2000 Dec 5;97(25):13766-71
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of Tlr1 polyclonal antibody (Cat # PAB3541) in mouse spleen tissue lysate. Tlr1 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with Tlr1 polyclonal antibody (Cat # PAB3541) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)