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Immunocytochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-130-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-130-C100, RRID:AB_2052675
- Product name
- Toll-like receptor 1 (human) monoclonal antibody (GD2.F4)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- GD2.F4
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.
Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas.
Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.
Regulation of Toll-like receptors in human monocytes and dendritic cells.
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses.
Guan Y, Ranoa DR, Jiang S, Mutha SK, Li X, Baudry J, Tapping RI
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5094-103
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5094-103
Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas.
Rydberg C, Månsson A, Uddman R, Riesbeck K, Cardell LO
Immunology 2009 Sep;128(1 Suppl):e600-11
Immunology 2009 Sep;128(1 Suppl):e600-11
Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.
Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, Weinberg A, Sieg SF
Proceedings of the National Academy of Sciences of the United States of America 2007 Nov 20;104(47):18631-5
Proceedings of the National Academy of Sciences of the United States of America 2007 Nov 20;104(47):18631-5
Regulation of Toll-like receptors in human monocytes and dendritic cells.
Visintin A, Mazzoni A, Spitzer JH, Wyllie DH, Dower SK, Segal DM
Journal of immunology (Baltimore, Md. : 1950) 2001 Jan 1;166(1):249-55
Journal of immunology (Baltimore, Md. : 1950) 2001 Jan 1;166(1):249-55
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses.
Wyllie DH, Kiss-Toth E, Visintin A, Smith SC, Boussouf S, Segal DM, Duff GW, Dower SK
Journal of immunology (Baltimore, Md. : 1950) 2000 Dec 15;165(12):7125-32
Journal of immunology (Baltimore, Md. : 1950) 2000 Dec 15;165(12):7125-32
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Supportive validation
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- Enzo Life Sciences (provider)
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- Experimental details
- Expression of TLR1 on monocytes. A mononuclear fraction from a healthy human donor was purified by centrifugal elution and stained with 15 µg/ml GD2.F4 or isotype control in the presence of 100 µg/ml normal human IgG. Binding was detected by anti-mouse FITC-conjugated secondary Ab, and the monocyte population was identified by forward and side scatter profiles.
