334702

antibody from BioLegend

Targeting: TLR6 CD286

Antibody data

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Validation data

Product number: 334702 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#334702, RRID:AB_1186021
Product name: Purified anti-human CD286 (TLR6)
Antibody type: Monoclonal
Antigen: Human TLR6 transfected Ba/F3 cells
Description: Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been identified. Toll-like receptor 6 (TLR6), known as CD286, is one of the important receptors. TLR6 is colocalized with TLR2 on the cell surface of monocytes/macrophages, dendritic cells, granulocytes. The TLR2/TLR6 complex plays a role in the innate immune response to diacylated lipoprotein and peptidoglycan antigens.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

TLR6 protein structure - 334702 shown in red.