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- References [15]
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- Product number
- 22240-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22240-1-AP, RRID:AB_11232032
- Product name
- TLR6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TLR6 antibody (Cat. #22240-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lacticaseibacillus rhamnosus LGG Suppresses Osteoclastogenesis via TLR6/NF-κB Modulation and Attenuates Ovariectomy-Induced Bone Loss in Mice.
Discovery of potent, selective human TLR1/2 agonists: N-quinoline-N'-(thiophen-2-yl)thiourea analogs for potential cancer immunotherapy.
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6.
METTL3 Promotes Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration by Regulating TLR2 m6A Methylation and Gut Microbiota.
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants.
Toll-like receptor signalling via IRAK4 affects epithelial integrity and tightness through regulation of junctional tension.
Neutrophil extracellular traps contribute to immunothrombosis formation via the STING pathway in sepsis-associated lung injury.
Identification and immunological evaluation of novel TLR2 agonists through structural optimization of Diprovocim.
Biomimetic Nanomedicine-Triggered in Situ Vaccination for Innate and Adaptive Immunity Activations for Bacterial Osteomyelitis Treatment.
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Design, Synthesis, and Structure-Activity Relationship of N-Aryl-N'-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy.
Pyridoxal-5'-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway.
Structure-activity relationship study and biological evaluation of SAC-Garlic acid conjugates as novel anti-inflammatory agents.
Toll-like receptor 6 V327M polymorphism is associated with an increased risk of Klebsiella pneumoniae infection.
Xiong K, Li J, Liu Y, Pan Y, Huang Y, Zhan D, Zhang L, Tang M, Li J, Sun H
Probiotics and antimicrobial proteins 2026 Apr;18(3):4523-4539
Probiotics and antimicrobial proteins 2026 Apr;18(3):4523-4539
Discovery of potent, selective human TLR1/2 agonists: N-quinoline-N'-(thiophen-2-yl)thiourea analogs for potential cancer immunotherapy.
Zeng X, Fu Q, Liao R, Mei H, Huang L, Zhu Z, Cheng K, Chen Z
European journal of medicinal chemistry 2025 Nov 5;297:117968
European journal of medicinal chemistry 2025 Nov 5;297:117968
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Qin X, Gao J, Liu X, Chen J, Song X
Biochemistry and biophysics reports 2025 Dec;44:102262
Biochemistry and biophysics reports 2025 Dec;44:102262
Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6.
Zhang X, He Y, Zhang X, Fu B, Song Z, Wang L, Fu R, Lu X, Xing J, Lv J, Guo M, Huo X, Liu X, Lu J, Du X, Ge Z, Chen Z, Li C
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2024 Mar;27(2):324-342
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2024 Mar;27(2):324-342
METTL3 Promotes Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration by Regulating TLR2 m6A Methylation and Gut Microbiota.
Ni S, Huang X, Li X, Shi C, Fan M, Zhao L, Rong Z, Zhang H
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Aug 1;79(8)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Aug 1;79(8)
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants.
Zhu Y, Liu B, Chen Z, Wang X, Wang Y, Zhang W, Wang S, Zhang M, Li Y
Bioorganic chemistry 2023 Dec;141:106823
Bioorganic chemistry 2023 Dec;141:106823
Toll-like receptor signalling via IRAK4 affects epithelial integrity and tightness through regulation of junctional tension.
Peterson J, Balogh Sivars K, Bianco A, Röper K
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
Neutrophil extracellular traps contribute to immunothrombosis formation via the STING pathway in sepsis-associated lung injury.
Zhu S, Yu Y, Qu M, Qiu Z, Zhang H, Miao C, Guo K
Cell death discovery 2023 Aug 25;9(1):315
Cell death discovery 2023 Aug 25;9(1):315
Identification and immunological evaluation of novel TLR2 agonists through structural optimization of Diprovocim.
Wang X, Wang Y, Zhu Y, Lei X, Zhang M, Li Y
European journal of medicinal chemistry 2022 Dec 5;243:114771
European journal of medicinal chemistry 2022 Dec 5;243:114771
Biomimetic Nanomedicine-Triggered in Situ Vaccination for Innate and Adaptive Immunity Activations for Bacterial Osteomyelitis Treatment.
Lin H, Yang C, Luo Y, Ge M, Shen H, Zhang X, Shi J
ACS nano 2022 Apr 26;16(4):5943-5960
ACS nano 2022 Apr 26;16(4):5943-5960
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis.
Xie X, Lv H, Liu C, Su X, Yu Z, Song S, Bian H, Tian M, Qin C, Qi J, Zhu Q
BMC medicine 2021 Oct 15;19(1):247
BMC medicine 2021 Oct 15;19(1):247
Design, Synthesis, and Structure-Activity Relationship of N-Aryl-N'-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy.
Chen Z, Zhang L, Yang J, Zheng L, Hu F, Duan S, Nandakumar KS, Liu S, Yin H, Cheng K
Journal of medicinal chemistry 2021 Jun 10;64(11):7371-7389
Journal of medicinal chemistry 2021 Jun 10;64(11):7371-7389
Pyridoxal-5'-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway.
Li C, Huang J, Zhu H, Shi Q, Li D, Ju X
Stem cells international 2019;2019:3121246
Stem cells international 2019;2019:3121246
Structure-activity relationship study and biological evaluation of SAC-Garlic acid conjugates as novel anti-inflammatory agents.
Bi J, Wang W, Du J, Chen K, Cheng K
European journal of medicinal chemistry 2019 Oct 1;179:233-245
European journal of medicinal chemistry 2019 Oct 1;179:233-245
Toll-like receptor 6 V327M polymorphism is associated with an increased risk of Klebsiella pneumoniae infection.
Yang H, Zhang X, Geng J, Zheng Z, Fu Q
The Pediatric infectious disease journal 2014 Nov;33(11):e310-5
The Pediatric infectious disease journal 2014 Nov;33(11):e310-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TLR6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TLR6. This antibody recognizes human, mouse antigen. The TLR6 antibody has been validated for the following applications: ELISA, WB analysis.
