FNab06886

antibody from FineTest Biotech

Targeting: PSMD14 pad1, POH1, Rpn11

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab06886 - Provider product page
Provider: FineTest Biotech
Product name: PSMD14 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks(DSBs): acts as a regulator of non-homologous end joining(NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: proteasome(prosome, macropain) 26S subunit, non-ATPase, 14
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

PSMD14 protein structure - FNab06886 shown in red.