HPA002114

antibody from Atlas Antibodies

Targeting: PSMD14 pad1, POH1, Rpn11

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA002114

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA002114, RRID:AB_1855850

Product name

Anti-PSMD14

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human PSMD14, Gene description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, Alternative Gene Names: pad1, POH1, Rpn11, Validated applications: ICC, IHC, WB, Uniprot ID: O00487, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation

Mamrosh J, Sherman D, Cohen J, Johnston J, Joubert M, Li J, Lipford J, Lomenick B, Moradian A, Prabhu S, Sweredoski M, Vander Lugt B, Verma R, Deshaies R
Science Advances 2023;9(25)

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PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERα

Yang P, Yang X, Wang D, Yang H, Li Z, Zhang C, Zhang S, Zhu J, Li X, Su P, Zhuang T
Oncogene 2023;43(4):248-264

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The prognostic role of PSMD14 in head and neck squamous cell carcinoma

Schnoell J, Scheiflinger A, Al-Gboore S, Kadletz-Wanke L, Kenner L, Heiduschka G, Jank B
Journal of Cancer Research and Clinical Oncology 2022;149(6):2483-2490

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Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness

Jing C, Duan Y, Zhou M, Yue K, Zhuo S, Li X, Liu D, Ye B, Lai Q, Li L, Yao X, Wei H, Zhang W, Wu Y, Wang X
Theranostics 2021;11(6):2655-2669

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POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Wang B, Xu X, Yang Z, Zhang L, Liu Y, Ma A, Xu G, Tang M, Jing T, Wu L, Liu Y
EBioMedicine 2019;41

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POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation

Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, Qiu B, Yang Z, Liu Y, Xia Q, Liu Y
Nature Communications 2015;6(1)

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Multiple components of the spliceosome regulate Mcl1 activity in neuroblastoma

Laetsch T, Liu X, Vu A, Sliozberg M, Vido M, Elci O, Goldsmith K, Hogarty M
Cell Death & Disease 2014;5(2):e1072-e1072

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Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.

Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22