Antibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 17023-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17023-1-AP, RRID:AB_2229737
- Product name
- Collagen Type VI antibody
- Antibody type
- Polyclonal
- Description
- Collagen Type VI antibody (Cat. #17023-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
Exon-Skipping for a Pathogenic COL6A1 Variant in Ullrich Congenital Muscular Dystrophy.
High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis.
In vivo rAAV-mediated human TGF-β overexpression reduces perifocal osteoarthritis and improves osteochondral repair in a large animal model at one year.
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Skeletal muscle proteome expression differentiates severity of cancer cachexia in mice and identifies loss of fragile X mental retardation syndrome-related protein 1.
Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.
Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.
Coaxial structured drug loaded dressing combined with induced stem cell differentiation for enhanced wound healing.
The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development.
Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis.
Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis.
Gapmer Antisense Oligonucleotides to Selectively Suppress the Mutant Allele in COL6A Genes in Dominant Ullrich Congenital Muscular Dystrophy.
MYCT1 Inhibits the Adhesion and Migration of Laryngeal Cancer Cells Potentially Through Repressing Collagen VI.
Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.
Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.
Proteomic analysis of mouse ovaries during the prepubertal stages.
Differential effect of extracellular matrix derived from papillary and reticular fibroblasts on epidermal development in vitro.
Authentication of collagen VI antibodies.
Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).
Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients.
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation.
Chen Y, Li J, Zhang X, Li S, Cheng Y, Fu X, Li J, Zhu L
Journal of advanced research 2024 May 13;
Journal of advanced research 2024 May 13;
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
Tian Z, Du Z, Bai G, Gong Q, You Y, Xu G, Liu J, Xiao M, Wang Y, He Y
Cancer gene therapy 2024 Apr;31(4):627-640
Cancer gene therapy 2024 Apr;31(4):627-640
Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
Liu Y, Murazzi I, Fuller AM, Pan H, Irizarry-Negron VM, Devine A, Katti R, Skuli N, Ciotti GE, Pak K, Pack MA, Simon MC, Weber K, Cooper K, Eisinger-Mathason TSK
Cancer research 2024 Apr 1;84(7):977-993
Cancer research 2024 Apr 1;84(7):977-993
Exon-Skipping for a Pathogenic COL6A1 Variant in Ullrich Congenital Muscular Dystrophy.
Aguti S, Guirguis F, Bönnemann C, Muntoni F, Bolduc V, Zhou H
Methods in molecular biology (Clifton, N.J.) 2023;2587:387-407
Methods in molecular biology (Clifton, N.J.) 2023;2587:387-407
High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer.
Zhang X, Liu J, Yang X, Jiao W, Shen C, Zhao X, Wang Y
Cell cycle (Georgetown, Tex.) 2023 Mar;22(5):610-618
Cell cycle (Georgetown, Tex.) 2023 Mar;22(5):610-618
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Chen WJ, Zhuang Y, Peng W, Cui W, Zhang SJ, Wang JW
Chinese medicine 2023 Jun 29;18(1):80
Chinese medicine 2023 Jun 29;18(1):80
Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis.
Zhang MH, Han XX, Lu Y, Deng JJ, Zhang WH, Mao JQ, Mi J, Ding WH, Wu MJ, Yu LM, Liu YH
Respiratory physiology & neurobiology 2023 Feb;308:103980
Respiratory physiology & neurobiology 2023 Feb;308:103980
In vivo rAAV-mediated human TGF-β overexpression reduces perifocal osteoarthritis and improves osteochondral repair in a large animal model at one year.
Schrenker S, Cucchiarini M, Goebel L, Oláh T, Venkatesan JK, Schmitt G, Speicher-Mentges S, Maihöfer J, Gao L, Zurakowski D, Menger MD, Laschke MW, Madry H
Osteoarthritis and cartilage 2023 Apr;31(4):467-481
Osteoarthritis and cartilage 2023 Apr;31(4):467-481
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.
Thant L, Kaku M, Kakihara Y, Mizukoshi M, Kitami M, Arai M, Kitami K, Kobayashi D, Yoshida Y, Maeda T, Saito I, Uoshima K, Saeki M
Frontiers in physiology 2022;13:899699
Frontiers in physiology 2022;13:899699
Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.
Feng Y, Zhu G, Chen R, Shi G, Peng M, Zhou Y, Fu W, Zhou P
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Biochemical and biophysical research communications 2022 Oct 20;626:44-50
Skeletal muscle proteome expression differentiates severity of cancer cachexia in mice and identifies loss of fragile X mental retardation syndrome-related protein 1.
Khamoui AV, Tokmina-Roszyk D, Feresin RG, Fields GB, Visavadiya NP
Proteomics 2022 May;22(10):e2100157
Proteomics 2022 May;22(10):e2100157
Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.
Liu X, Li N, Zhang C, Wu X, Zhang S, Dong G, Liu G
Translational oncology 2022 May;19:101389
Translational oncology 2022 May;19:101389
Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.
Ouni E, Nedbal V, Da Pian M, Cao H, Haas KT, Peaucelle A, Van Kerk O, Herinckx G, Marbaix E, Dolmans MM, Tuuri T, Otala M, Amorim CA, Vertommen D
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:91-120
Matrix biology : journal of the International Society for Matrix Biology 2022 May;109:91-120
Coaxial structured drug loaded dressing combined with induced stem cell differentiation for enhanced wound healing.
Gao C, Zhang L, Wang J, Cheng Y, Chen Z, Yang R, Zhao G
Biomaterials advances 2022 Mar;134:112542
Biomaterials advances 2022 Mar;134:112542
The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development.
De A, Morales JE, Chen Z, Sebastian S, McCarty JH
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis.
Angelini A, Ortiz-Urbina J, Trial J, Reddy AK, Malovannaya A, Jain A, Entman ML, Taffet GE, Cieslik KA
American journal of physiology. Heart and circulatory physiology 2022 Aug 1;323(2):H285-H300
American journal of physiology. Heart and circulatory physiology 2022 Aug 1;323(2):H285-H300
Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis.
Li M, Li X, Liu B, Lv L, Wang W, Gao D, Zhang Q, Jiang J, Chai M, Yun Z, Tan Y, Gong F, Wu Z, Zhu Y, Ma J, Leng L
Frontiers in cell and developmental biology 2021;9:783456
Frontiers in cell and developmental biology 2021;9:783456
Gapmer Antisense Oligonucleotides to Selectively Suppress the Mutant Allele in COL6A Genes in Dominant Ullrich Congenital Muscular Dystrophy.
Aguti S, Marrosu E, Muntoni F, Zhou H
Methods in molecular biology (Clifton, N.J.) 2020;2176:221-230
Methods in molecular biology (Clifton, N.J.) 2020;2176:221-230
MYCT1 Inhibits the Adhesion and Migration of Laryngeal Cancer Cells Potentially Through Repressing Collagen VI.
Wang PP, Ding SY, Sun YY, Li YH, Fu WN
Frontiers in oncology 2020;10:564733
Frontiers in oncology 2020;10:564733
Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.
Kashpur O, Smith A, Gerami-Naini B, Maione AG, Calabrese R, Tellechea A, Theocharidis G, Liang L, Pastar I, Tomic-Canic M, Mooney D, Veves A, Garlick JA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1262-1277
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1262-1277
Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.
Wang H, Ning T, Song C, Luo X, Xu S, Zhang X, Deng Z, Ma D, Wu B
Journal of cellular physiology 2019 Aug;234(8):12897-12909
Journal of cellular physiology 2019 Aug;234(8):12897-12909
Proteomic analysis of mouse ovaries during the prepubertal stages.
Xiong J, Wu M, Zhang Q, Zhang C, Xiong G, Ma L, Lu Z, Wang S
Experimental cell research 2019 Apr 15;377(1-2):36-46
Experimental cell research 2019 Apr 15;377(1-2):36-46
Differential effect of extracellular matrix derived from papillary and reticular fibroblasts on epidermal development in vitro.
Janson D, Rietveld M, Mahé C, Saintigny G, El Ghalbzouri A
European journal of dermatology : EJD 2017 Jun 1;27(3):237-246
European journal of dermatology : EJD 2017 Jun 1;27(3):237-246
Authentication of collagen VI antibodies.
Endicott J, Holden P, Fitzgerald J
BMC research notes 2017 Jul 29;10(1):358
BMC research notes 2017 Jul 29;10(1):358
Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).
García-Palmero I, Torres S, Bartolomé RA, Peláez-García A, Larriba MJ, Lopez-Lucendo M, Peña C, Escudero-Paniagua B, Muñoz A, Casal JI
Oncogene 2016 Oct 6;35(40):5224-5236
Oncogene 2016 Oct 6;35(40):5224-5236
Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients.
Wan F, Wang H, Shen Y, Zhang H, Shi G, Zhu Y, Dai B, Ye D
Oncotarget 2015 Sep 29;6(29):27378-87
Oncotarget 2015 Sep 29;6(29):27378-87
Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.
Zhu YP, Wan FN, Shen YJ, Wang HK, Zhang GM, Ye DW
Oncotarget 2015 Jun 10;6(16):14488-96
Oncotarget 2015 Jun 10;6(16):14488-96
A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation.
Paez-Cortez J, Krishnan R, Arno A, Aven L, Ram-Mohan S, Patel KR, Lu J, King OD, Ai X, Fine A
PloS one 2013;8(9):e74469
PloS one 2013;8(9):e74469
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17023-1-AP(COL6A1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17023-1-AP(COL6A1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17023-1-AP(COL6A1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue