orb66727

antibody from Biorbyt

Targeting: DNMT1 CXXC9, DNMT, MCMT

Western blot (Data presented on provider website)

Antibody Data

Product number

orb66727

Provider

Biorbyt

Product name

DNMT1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to DNMT1.DNA (cytosine-5)-methyltransferase 1 (DNMT1) plays a role in methylating CpG residues.Preferentially methylates hemimethylated DNA and regulates tissue-specific patterns of methylatedcytosine residues. During S phase of the cell cycle DNMT1 localizes at replication sites conservingmethylation patterns in the newly synthesized strand, maintaining epigenetic inheritance. During G2and M phases of the cell cycle, DNMT1 associates with chromatin maintaining DNA methylationirrespective of replication. Atypical DNA methylation patterns have been shown to be associated withcertain human tumors and developmental abnormalities.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C