Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb66727 - Provider product page
- Provider
- Biorbyt
- Product name
- DNMT1 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal to DNMT1.DNA (cytosine-5)-methyltransferase 1 (DNMT1) plays a role in methylating CpG residues.Preferentially methylates hemimethylated DNA and regulates tissue-specific patterns of methylatedcytosine residues. During S phase of the cell cycle DNMT1 localizes at replication sites conservingmethylation patterns in the newly synthesized strand, maintaining epigenetic inheritance. During G2and M phases of the cell cycle, DNMT1 associates with chromatin maintaining DNA methylationirrespective of replication. Atypical DNA methylation patterns have been shown to be associated withcertain human tumors and developmental abnormalities.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 ul
- Storage
- -20°C
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