Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- PAB1660 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1660, RRID:AB_1238042
- Product name
- DNMT1 (phospho S714) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of DNMT1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.
Peterson EJ, Bögler O, Taylor SM
Cancer research 2003 Oct 15;63(20):6579-82
Cancer research 2003 Oct 15;63(20):6579-82
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, Huang TH
Cancer research 2003 Oct 1;63(19):6110-5
Cancer research 2003 Oct 1;63(19):6110-5
Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.
Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H, Hirohashi S
International journal of cancer 2003 Jul 1;105(4):527-32
International journal of cancer 2003 Jul 1;105(4):527-32
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Dot blot analysis of DNMT1 (phospho S714) polyclonal antibody (Cat # PAB1660) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 ug/mL.
- Validation comment
- Dot Blot (Peptide)