Antibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- ABIN1027706 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 620-950) antibody
- Antibody type
- Monoclonal
- Description
- Protein G Purified
- Reactivity
- Human, Mouse, Zebrafish
- Host
- Mouse
- Epitope
- AA 620-950
- Isotype
- IgG
- Antibody clone number
- 4G11-C7
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
Dissecting de novo methylation.
Cloning, expression and chromosome locations of the human DNMT3 gene family.
Isolation and characterization of the cDNA encoding human DNA methyltransferase.
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases.
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP
Nature genetics 2000 Jul;25(3):338-42
Nature genetics 2000 Jul;25(3):338-42
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
Okano M, Bell DW, Haber DA, Li E
Cell 1999 Oct 29;99(3):247-57
Cell 1999 Oct 29;99(3):247-57
Dissecting de novo methylation.
Reik W, Kelsey G, Walter J
Nature genetics 1999 Dec;23(4):380-2
Nature genetics 1999 Dec;23(4):380-2
Cloning, expression and chromosome locations of the human DNMT3 gene family.
Xie S, Wang Z, Okano M, Nogami M, Li Y, He WW, Okumura K, Li E
Gene 1999 Aug 5;236(1):87-95
Gene 1999 Aug 5;236(1):87-95
Isolation and characterization of the cDNA encoding human DNA methyltransferase.
Yen RW, Vertino PM, Nelkin BD, Yu JJ, el-Deiry W, Cumaraswamy A, Lennon GG, Trask BJ, Celano P, Baylin SB
Nucleic acids research 1992 May 11;20(9):2287-91
Nucleic acids research 1992 May 11;20(9):2287-91
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases.
Bestor T, Laudano A, Mattaliano R, Ingram V
Journal of molecular biology 1988 Oct 20;203(4):971-83
Journal of molecular biology 1988 Oct 20;203(4):971-83
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