M00563

antibody from Boster Biological Technology
Targeting: FANCD2 FA-D2, FACD, FAD, FANCD
Provider product page for M00563
Western blot
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
M00563 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-FANCD2 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for FANCD2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat FANCD2 information: Molecular Weight: 164128 MW; Subcellular Localization: Nucleus . Concentrates in nuclear foci during S phase and upon genotoxic stress. At the onset of mitosis, excluded from chromosomes and diffuses into the cytoplasm, returning to the nucleus at the end of cell division. Observed in a few spots localized in pairs on the sister chromatids of mitotic chromosome arms and not centromeres, one on each chromatids. These foci coincide with common fragile sites and could be sites of replication fork stalling. The foci are frequently interlinked through BLM-associated ultra-fine DNA bridges. Following aphidicolin treatment, targets chromatid gaps and breaks; Tissue Specificity: Highly expressed in germinal center cells of the spleen, tonsil, and reactive lymph nodes, and in the proliferating basal layer of squamous epithelium of tonsil, esophagus, oropharynx, larynx and cervix. Expressed in cytotrophoblastic cells of the placenta and exocrine cells of the pancreas (at prot
Reactivity
Human, Mouse, Rat
Host
Rabbit
Antibody clone number
GCE-6
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
FANCD2 protein structure - M00563 shown in red.