FNab03006

antibody from FineTest Biotech

Targeting: FANCD2 FA-D2, FACD, FAD, FANCD

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Immunoprecipitation

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Validation data

Product number: FNab03006 - Provider product page
Provider: FineTest Biotech
Product name: FANCD2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.The antibody recognize both un-phospho and phospho-Ser(330) of FANCD2.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: Fanconi anemia, complementation gro up D2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

FANCD2 protein structure - FNab03006 shown in red.