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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunoprecipitation [1]
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- Product number
- MAB0074 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB0074, RRID:AB_1019029
- Product name
- TERF2 monoclonal antibody, clone 4A794.15
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant TERF2.
- Isotype
- IgG
- Antibody clone number
- 4A794.15
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine.
Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
FLASH is required for histone transcription and S-phase progression.
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.
TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells.
Zhang YW, Zhang ZX, Miao ZH, Ding J
Molecular pharmacology 2008 Mar;73(3):824-32
Molecular pharmacology 2008 Mar;73(3):824-32
Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H
Experimental cell research 2008 Mar 10;314(5):1115-24
Experimental cell research 2008 Mar 10;314(5):1115-24
FLASH is required for histone transcription and S-phase progression.
Barcaroli D, Bongiorno-Borbone L, Terrinoni A, Hofmann TG, Rossi M, Knight RA, Matera AG, Melino G, De Laurenzi V
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 3;103(40):14808-12
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 3;103(40):14808-12
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.
Raz V, Carlotti F, Vermolen BJ, van der Poel E, Sloos WC, Knaän-Shanzer S, de Vries AA, Hoeben RC, Young IT, Tanke HJ, Garini Y, Dirks RW
Journal of cell science 2006 Oct 15;119(Pt 20):4247-56
Journal of cell science 2006 Oct 15;119(Pt 20):4247-56
TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells.
Biroccio A, Rizzo A, Elli R, Koering CE, Belleville A, Benassi B, Leonetti C, Stevens MF, D'Incalci M, Zupi G, Gilson E
European journal of cancer (Oxford, England : 1990) 2006 Aug;42(12):1881-8
European journal of cancer (Oxford, England : 1990) 2006 Aug;42(12):1881-8
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunoprecipitation (IP) / Western Blot (WB) Analysis of TERF2 in HL-60 cells : (Lane 1) IP with mouse TERF2 monoclonal antibody, clone 4A794.15 (Cat # MAB0074) . (Lane 2) IP with control mouse IgG. (Lane 3) IP with goat anti-TRF2. (Lane 4) IP with pre-immune goat Ig. (Lanes 1-4) WB with TERF2 monoclonal antibody, clone 4A794.15 (Cat # MAB0074) . TRF2 is detected as an ~ 66 kD protein.
- Validation comment
- Immunoprecipitation
