66893-1-Ig

antibody from Proteintech Group

Targeting: TERF2 TRBF2, TRF2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66893-1-Ig

Provider

Proteintech Group

Product name

TERF2 antibody

Antibody type

Monoclonal

Description

TERF2 antibody (Cat. #66893-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

5B1E1

Vial size

20ul, 150ul

References

Submitted references

PRKN-Mediated Ubiquitin-Proteasome Degradation of METTL3 Promotes Cellular Senescence.

Chen L, Zhang C, Ge Y, Zhou H, Yang S, Wei W, Zhou Q, Xiao K, Huang G, Li X, Wang J, Zheng J, Gu R, Ju Z, Wu S
Aging cell 2026 Jan;25(1):e70347

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Novel telomere-targeting dual-pharmacophore dinucleotide prodrugs for anticancer therapy.

Mender I, Girotti R, Gryaznov S
Nucleic acids research 2025 Jun 20;53(12)

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SUMOylation of TP53INP1 is involved in miR-30a-5p-regulated heart senescence.

Hong YX, Wu C, Li JZ, Song F, Hu Y, Han Y, Mao YJ, Wu WY, Wang Y, Li G
Experimental & molecular medicine 2024 Nov;56(11):2519-2534

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Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence.

Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA
Nature communications 2024 May 14;15(1):4061

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miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2.

Jiang Y, Xu J, Zeng H, Lin Z, Yi Q, Guo J, Xiao F
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):607-620

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Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B-Lamin B1 Interaction in Alcoholic Fatty Liver Disease.

Qi X, Zheng S, Ma M, Lian N, Wang H, Chen L, Song A, Lu C, Zheng S, Jin H
Frontiers in pharmacology 2022;13:912825

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Regulation of telomere homeostasis and genomic stability in cancer by N (6)-adenosine methylation (m(6)A).

Lee JH, Hong J, Zhang Z, de la Peña Avalos B, Proietti CJ, Deamicis AR, Guzmán G P, Lam HM, Garcia J, Roudier MP, Sisk AE, De La Rosa R, Vu K, Yang M, Liao Y, Scheirer J, Pechacek D, Yadav P, Rao MK, Zheng S, Johnson-Pais TL, Leach RJ, Elizalde PV, Dray E, Xu K
Science advances 2021 Jul;7(31)