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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16947-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16947-1-AP, RRID:AB_2245654
- Product name
- DCTN6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DCTN6 antibody (Cat. #16947-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains.
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation.
Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles.
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Sharoar MG, Zhou J, Benoit M, He W, Yan R
Neurobiology of aging 2021 Nov;107:21-29
Neurobiology of aging 2021 Nov;107:21-29
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation.
di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X
Current biology : CB 2017 Aug 21;27(16):2452-2464.e8
Current biology : CB 2017 Aug 21;27(16):2452-2464.e8
Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles.
Cavolo SL, Zhou C, Ketcham SA, Suzuki MM, Ukalovic K, Silverman MA, Schroer TA, Levitan ES
Molecular biology of the cell 2015 Jul 15;26(14):2664-72
Molecular biology of the cell 2015 Jul 15;26(14):2664-72
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Yeh TY, Kowalska AK, Scipioni BR, Cheong FK, Zheng M, Derewenda U, Derewenda ZS, Schroer TA
The EMBO journal 2013 Apr 3;32(7):1023-35
The EMBO journal 2013 Apr 3;32(7):1023-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 16947-1-AP(DCTN6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 16947-1-AP(DCTN6 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DCTN6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DCTN6. This antibody recognizes human, mouse, rat antigen. The DCTN6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
