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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16947-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16947-1-AP, RRID:AB_2245654
- Product name
- DCTN6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DCTN6 antibody (Cat. #16947-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection.
Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains.
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation.
Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles.
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Sherry J, Pawar KI, Dolat L, Smith E, Chang IC, Pha K, Kaake R, Swaney DL, Herrera C, McMahon E, Bastidas RJ, Johnson JR, Valdivia RH, Krogan NJ, Elwell CA, Verba K, Engel JN
Cell reports 2025 Apr 22;44(4):115509
Cell reports 2025 Apr 22;44(4):115509
Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains.
Sharoar MG, Zhou J, Benoit M, He W, Yan R
Neurobiology of aging 2021 Nov;107:21-29
Neurobiology of aging 2021 Nov;107:21-29
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation.
di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X
Current biology : CB 2017 Aug 21;27(16):2452-2464.e8
Current biology : CB 2017 Aug 21;27(16):2452-2464.e8
Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles.
Cavolo SL, Zhou C, Ketcham SA, Suzuki MM, Ukalovic K, Silverman MA, Schroer TA, Levitan ES
Molecular biology of the cell 2015 Jul 15;26(14):2664-72
Molecular biology of the cell 2015 Jul 15;26(14):2664-72
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Yeh TY, Kowalska AK, Scipioni BR, Cheong FK, Zheng M, Derewenda U, Derewenda ZS, Schroer TA
The EMBO journal 2013 Apr 3;32(7):1023-35
The EMBO journal 2013 Apr 3;32(7):1023-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 16947-1-AP(DCTN6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 16947-1-AP(DCTN6 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DCTN6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DCTN6. This antibody recognizes human, mouse, rat antigen. The DCTN6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
