BS4649

antibody from Bioworld Technology, Inc
Targeting: APC DP2, DP2.5, DP3, PPP1R46
Provider product page for BS4649

Antibody data

Product number
BS4649 - Provider product page
Provider
Bioworld Technology, Inc
Product name
APC (phospho S2054) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human APC around the phosphorylation site of Serine 2054.
Description
Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ?-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
APC protein structure - BS4649 shown in red.