AMM03266G

antibody from Leading Biology

Targeting: APC DP2, DP2.5, DP3, PPP1R46

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

AMM03266G

Provider

Leading Biology

Product name

APC Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3E3

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.