Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- LS-B3568 - Provider product page
- Provider
- LSBio
- Product name
- KLB / Beta Klotho Antibody (Internal) LS-B3568
- Antibody type
- Polyclonal
- Description
- Immunoaffinity purified
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Storage
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Submitted references MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function.
Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.
Fu T, Seok S, Choi S, Huang Z, Suino-Powell K, Xu HE, Kemper B, Kemper JK
Molecular and cellular biology 2014 Nov 15;34(22):4130-42
Molecular and cellular biology 2014 Nov 15;34(22):4130-42
Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.
Fu T, Choi SE, Kim DH, Seok S, Suino-Powell KM, Xu HE, Kemper JK
Proceedings of the National Academy of Sciences of the United States of America 2012 Oct 2;109(40):16137-42
Proceedings of the National Academy of Sciences of the United States of America 2012 Oct 2;109(40):16137-42
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Supportive validation
- Submitted by
- LSBio (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.