TAB-1251CL

antibody from Creative Biolabs

Targeting: KLB

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

TAB-1251CL

Provider

Creative Biolabs

Product name

Mouse Anti-KLB Recombinant Antibody (TAB-1251CL)

Antibody type

Monoclonal

Description

This product is a recombinant mouse antibody that recognizes Beta klotho (KLB, a single-pass type I membrane protein). KLB is mainly expressed in liver, pancreas and adipose tissue. This antibody could induce intracellular signaling transduction in human and cynomolgus monkey, which leads to ERK and then Elk1 phosphorylation. Binding affinity measurements were made in Biacore-based assays, K_D values of this mAb to human KLB and cynomolgus monkey KLB are about 1 pM and 0.72 nM respectively.

Reactivity

Human, Simian

Host

Mouse

Storage

Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.