Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12088-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12088-1-AP, RRID:AB_2178460
- Product name
- REEP6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated REEP6 antibody (Cat. #12088-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references REEP6 deficiency leads to retinal degeneration through disruption of ER homeostasis and protein trafficking.
Nasal neuron PET imaging quantifies neuron generation and degeneration.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa.
Agrawal SA, Burgoyne T, Eblimit A, Bellingham J, Parfitt DA, Lane A, Nichols R, Asomugha C, Hayes MJ, Munro PM, Xu M, Wang K, Futter CE, Li Y, Chen R, Cheetham ME
Human molecular genetics 2017 Jul 15;26(14):2667-2677
Human molecular genetics 2017 Jul 15;26(14):2667-2677
Nasal neuron PET imaging quantifies neuron generation and degeneration.
Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM
The Journal of clinical investigation 2017 Feb 1;127(2):681-694
The Journal of clinical investigation 2017 Feb 1;127(2):681-694
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa.
Arno G, Agrawal SA, Eblimit A, Bellingham J, Xu M, Wang F, Chakarova C, Parfitt DA, Lane A, Burgoyne T, Hull S, Carss KJ, Fiorentino A, Hayes MJ, Munro PM, Nicols R, Pontikos N, Holder GE, UKIRDC, Asomugha C, Raymond FL, Moore AT, Plagnol V, Michaelides M, Hardcastle AJ, Li Y, Cukras C, Webster AR, Cheetham ME, Chen R
American journal of human genetics 2016 Dec 1;99(6):1305-1315
American journal of human genetics 2016 Dec 1;99(6):1305-1315
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12088-1-AP(REEP6 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The REEP6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human REEP6. This antibody recognizes human,mouse,rat antigen. The REEP6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.