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- References [16]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11247-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11247-2-AP, RRID:AB_2264940
- Product name
- MUM1/IRF4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MUM1/IRF4 antibody (Cat. #11247-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Metabolic crosstalk between skeletal muscle cells and liver through IRF4-FSTL1 in nonalcoholic steatohepatitis.
The selective activator protein-1 inhibitor T-5224 regulates the IRF4/MYC axis and exerts cooperative antimyeloma activity with bortezomib.
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation.
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
Cayratia japonica Prevents Ulcerative Colitis by Promoting M2 Macrophage Polarization through Blocking the TLR4/MAPK/NF-κB Pathway.
A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation.
Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome.
Maggot treatment promotes healing of diabetic foot ulcer wounds possibly by upregulating Treg levels.
IRF-4 deficiency reduces inflammation and kidney fibrosis after folic acid-induced acute kidney injury.
IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway.
Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis.
MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression.
Tang L, Zhang H, Zhou F, Wei Q, Du M, Wu J, Li C, Luo W, Zhou J, Wang X, Chen Z, Zhang Y, Huang Z, Wu Z, Wen Y, Jiang H, Liao D, Kou H, Xiong W, Mei H, Hu Y
Cancer communications (London, England) 2024 Mar;44(3):408-432
Cancer communications (London, England) 2024 Mar;44(3):408-432
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Stachowicz-Suhs M, Łabędź N, Anisiewicz A, Banach J, Kłopotowska D, Milczarek M, Piotrowska A, Dzięgiel P, Maciejczyk A, Matkowski R, Wietrzyk J
Scientific reports 2024 Feb 15;14(1):3778
Scientific reports 2024 Feb 15;14(1):3778
Metabolic crosstalk between skeletal muscle cells and liver through IRF4-FSTL1 in nonalcoholic steatohepatitis.
Guo S, Feng Y, Zhu X, Zhang X, Wang H, Wang R, Zhang Q, Li Y, Ren Y, Gao X, Bian H, Liu T, Gao H, Kong X
Nature communications 2023 Sep 28;14(1):6047
Nature communications 2023 Sep 28;14(1):6047
The selective activator protein-1 inhibitor T-5224 regulates the IRF4/MYC axis and exerts cooperative antimyeloma activity with bortezomib.
Tang S, Zhang F, Li J, Dong H, Yang Q, Liu J, Fu Y
Chemico-biological interactions 2023 Oct 1;384:110687
Chemico-biological interactions 2023 Oct 1;384:110687
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.
Flümann R, Hansen J, Pelzer BW, Nieper P, Lohmann T, Kisis I, Riet T, Kohlhas V, Nguyen PH, Peifer M, Abedpour N, Bosco G, Thomas RK, Kochanek M, Knüfer J, Jonigkeit L, Beleggia F, Holzem A, Büttner R, Lohneis P, Meinel J, Ortmann M, Persigehl T, Hallek M, Calado DP, Chmielewski M, Klein S, Göthert JR, Chapuy B, Zevnik B, Wunderlich FT, von Tresckow B, Jachimowicz RD, Melnick AM, Reinhardt HC, Knittel G
Blood cancer discovery 2023 Jan 6;4(1):78-97
Blood cancer discovery 2023 Jan 6;4(1):78-97
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation.
Xie J, Du Y, Liu D, Wu J, Yang K, He X, Zhao J, Hong P, Liao K, Zhang H, Hong Y, Teijaro JR, Kang SG, Xiao C, Liu WH
Cell reports 2023 Aug 29;42(8):112968
Cell reports 2023 Aug 29;42(8):112968
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
Liao W, Foo HYC, Tran TNQ, Chai CLL, Wong WSF
British journal of pharmacology 2023 Apr;180(8):1056-1071
British journal of pharmacology 2023 Apr;180(8):1056-1071
Cayratia japonica Prevents Ulcerative Colitis by Promoting M2 Macrophage Polarization through Blocking the TLR4/MAPK/NF-κB Pathway.
Sun J, Zhao P, Ding X, Li F, Jiang J, Huang H, Ji L
Mediators of inflammation 2022;2022:1108569
Mediators of inflammation 2022;2022:1108569
A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation.
Wu J, Yang K, Cai S, Zhang X, Hu L, Lin F, Wu SQ, Xiao C, Liu WH, Han J
Nature communications 2022 Nov 28;13(1):7321
Nature communications 2022 Nov 28;13(1):7321
Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome.
Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X
Diabetes 2022 Nov 1;71(11):2256-2271
Diabetes 2022 Nov 1;71(11):2256-2271
Maggot treatment promotes healing of diabetic foot ulcer wounds possibly by upregulating Treg levels.
Zhang J, Chen J, Gao C, Sun X, Wang L, Hu Z, Li G, Wang J, Wang A
Diabetes research and clinical practice 2022 Feb;184:109187
Diabetes research and clinical practice 2022 Feb;184:109187
IRF-4 deficiency reduces inflammation and kidney fibrosis after folic acid-induced acute kidney injury.
Chen M, Wen X, Gao Y, Liu B, Zhong C, Nie J, Liang H
International immunopharmacology 2021 Nov;100:108142
International immunopharmacology 2021 Nov;100:108142
IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway.
Zhu X, Yao T, Wang R, Guo S, Wang X, Zhou Z, Zhang Y, Zhuo X, Wang R, Li JZ, Liu T, Kong X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001502
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct;7(19):2001502
Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis.
Dong J, Ma Q
Nanotoxicology 2018 Mar;12(2):153-168
Nanotoxicology 2018 Mar;12(2):153-168
MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression.
Jia A, Wang Y, Sun W, Xiao B, Wei Y, Qiu L, Mu L, Xu L, Li J, Zhang X, Liu D, Peng C, Zhang D, Xiang X
Mediators of inflammation 2017;2017:6249685
Mediators of inflammation 2017;2017:6249685
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 11247-2-AP( IRF4 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IRF4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IRF4. This antibody recognizes human, mouse antigen. The IRF4 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
