Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7846 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-IRF4 Monoclonal antibody, clone 4F5 [PE]
- Antibody type
- Monoclonal
- Description
- The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6
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