CABT-BL7847

antibody from Creative Diagnostics

Targeting: IRF4 LSIRF, MUM1

No application information provided.

Antibody Data

Product number

CABT-BL7847

Provider

Creative Diagnostics

Product name

Anti-IRF4 Monoclonal antibody, clone 4F5

Antibody type

Monoclonal

Description

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6