Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01918G - Provider product page
- Provider
- Leading Biology
- Product name
- IRF4 Antibody (clone 2F2)
- Antibody type
- Monoclonal
- Description
- Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 2F2
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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