66451-1-Ig

antibody from Proteintech Group

Targeting: IRF4 LSIRF, MUM1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66451-1-Ig

Provider

Proteintech Group

Product name

IRF4 antibody

Antibody type

Monoclonal

Description

IRF4 antibody (Cat. #66451-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1A12D5

Vial size

20ul, 150ul

References

Submitted references

Urban particulate matter induces NLRP3/NLRP6 inflammasomes, autophagy, senescence and fibrotic responses by increasing CSF2 signaling in kidney cells.

Su RY, Chuang HC, Zheng CM, Ho LJ, Chen YJ, Lee YH, Chiu HW
Free radical biology & medicine 2026 Jun;249:1-13

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Endogenous protein tagging coupled with a CRISPR screening approach identifies UBE3C as a potential MYC oncogene regulator.

Seibert M, Kurrle N, Kaleab S, Wempe F, von Metzler I, Serve H, Schnütgen F
Scientific reports 2026 Apr 11;16(1)

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LAMP5 modulates IRF4 stability and nuclear transport: a critical mechanism in myeloma progression and therapy.

Li Z, Liu R, Fang Z, Chen R, Yang D, Li Y, Liu S, Wang C, Liu H
Oncogene 2025 Oct;44(38):3553-3567

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Impact of gut microbiome on radiotherapy and immunotherapy efficacy in microsatellite-stable colorectal cancer: role of propionic acid and B. fragilis.

Yu L, Guo Q, Gu X, Wang Z, Li J, Wang X, Xu Z, Wang Y, Zhang Y, Zhang Y, Ding Y, Chen Z, Chen K, Ding Y
British journal of cancer 2025 Oct;133(7):956-969

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Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus.

Zhang S, Zhong R, Zhou M, Li K, Lv H, Wang H, Xu Y, Liu D, Ma Q, Chen L, Zhang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415948

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Irf4 participates in benzene-induced hematopoietic senescence through mitochondrial ROS-dependent BCAA catabolism.

Liu Z, Wang J, Zhang W, Kang H, Huang D, Wang Z, Jiang G, Gao A
Toxicology 2025 Dec;518:154271

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TBK1 is involved in M-CSF-induced macrophage polarization through mediating the IRF5/IRF4 axis.

Li Y, Ji L, Liu C, Li J, Wen D, Li Z, Yu L, Guo M, Zhang S, Duan W, Yi L, Bi Y, Bu H, Li C, Liu Y
The FEBS journal 2024 Dec;291(23):5214-5235

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Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.

Mou Y, Wu GR, Wang Q, Pan T, Zhang L, Xu Y, Xiong W, Zhou Q, Wang Y
Bioengineering & translational medicine 2022 May;7(2):e10280

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RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.

Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162