Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 646402 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#646402, RRID:AB_2280462
- Product name
- Purified anti-IRF4
- Antibody type
- Monoclonal
- Antigen
- GST fusion protein containing C-terminal of murine IRF4
- Description
- The IRF family consists of at least 9 members. IRF4 and IRF8 are highly homolgous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays essential role for macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.
- Reactivity
- Human, Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Western blot analysis of Daudi (lane 1) , Raji(lane 2) and A20 (lane 3) cells using IRF4 antibody (clone IRF4.3E4). β-actin antibody (poly6221) was used as loading control.
- Conjugate
- Unconjugated