Ab116484

antibody from Aladdin Scientific

Targeting: IRF4 LSIRF, MUM1

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Product number: Ab116484 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant IRF4 Antibody
Antibody type: Recombinant
Description: Rabbit anti Human IRF4 Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500 Ð 1/10000Protein FunctionTranscriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 144-450
Vial size: 100_l,10_l,1ml,50_l
Concentration: 0,25 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

IRF4 protein structure - Ab116484 shown in red.