SSRP1

gene product
FACT80
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008]
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255 antibodies from 29 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
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Invitrogen Antibodies
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Abnova Corporation
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Atlas Antibodies
1 antibody
Acris Antibodies GmbH
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Bioworld Technology, Inc
1 antibody
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Cell Signaling Technology, Inc
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RabMAbs
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United States Biological
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MyBioSource
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Creative Biolabs
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ProSci
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Boster Biological Technology
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Exalpha Biologicals, Inc.
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Sigma-Aldrich
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Abbexa
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