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- Antigen structure
- References [106]
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- Product number
- 55028-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55028-1-AP, RRID:AB_10858390
- Product name
- PFKM antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PFKM antibody (Cat. #55028-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination.
USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice.
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
N-nitrosodimethylamine increased glucose production by promoting hyperglycemia in hepatocyte via AMPK signaling pathway in vivo and in vitro.
Porcine epidemic diarrhea virus promotes viral replication via ROS/HIF-1α-mediated glycolysis.
High-Fat Diet Promotes Glycolysis in Hepatocellular Carcinoma by Suppressing Hepatic Kisspeptin Signaling in Mice.
Cancer-Associated fibroblasts regulate the development of cholangiocarcinoma through IL-6/STAT3/AKR1C3 signaling axis.
The glycolytic enzyme PFKM promotes renal fibrosis by activating the NF-κB pathway via lactate-mediated H3K18 lactylation.
AFP confers the resistance of lenvatinib in hepatocellular carcinoma by activating PI3K/AKT/LDHA signaling axis.
Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion.
Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats.
Artemether ameliorates type 1 diabetes mellitus by modulating glycolipid metabolism in skeletal muscle.
Integrated Multilayer Omics Reveals the Underlying Mechanisms in Xylazine-Related Heart Injury in Rats.
PKM2 alleviates mitochondrial oxidative stress and neuronal apoptosis through metabolic and non-metabolic pathways to protect SOD1(G93A) mice.
Astragaloside IV alleviates radiation-induced heart disease by regulating energy metabolism.
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1-Mediated Phosphoenolpyruvate Production.
m(6)A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis.
IL17A Mediates Glycolysis-Dependent Primary Angiogenesis and Exacerbates Ischemic Stroke Injury.
Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia.
The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO(2) on Lactate Production in TM4 Cells.
Knockdown of SESN2 Exacerbates Cerebral Ischemia-Reperfusion Injury Through Enhancing Glycolysis via the mTOR/HIF-1α Pathway.
PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer.
Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O(2)) during long-term Adipose-Derived Stem/Stromal cell culture.
Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia-reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle.
RB1 controls differentiation through positive regulation of phosphoglycerate mutases.
PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate.
SESN2 mediates resistance training-induced improvements in exercise performance and energy metabolism in C57BL/6J mice.
Baicalein suppresses inflammation and attenuates acute lung injury by inhibiting glycolysis via HIF‑1α signaling.
Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction.
Juglone targets MMP-1 to inhibit gastric cancer progression.
m6A-mediated regulation of ECA39 promotes renal fibrosis in chronic kidney disease by enhancing glycolysis and epithelial-mesenchymal transition.
Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway.
Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome.
Fenofibrate Differently Affects the Heart's Morphology and Metabolism in Young and Old Rats.
TXNIP participates in the pathogenesis of PCOS by regulating glycolysis in granulosa cells.
Study on the mechanisms of defective spermatogenesis induced by TiO(2) NPs based on 3D blood-testis barrier microfluidic chip.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Dietary pectin and inulin: A promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4(+) T cell reconstitution.
Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1.
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Physiological and molecular predictors of cycling sprint performance.
Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands.
Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling.
Proteomic analysis of mouse liver lesions at all three stages of Echinococcus granulosus infection.
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Dynamic changes of protein lactylation and their correlations with the glycolytic process during the postmortem acidification of broiler breast.
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
Neuroprotective Potential of Nitroglycerin in Ischemic Stroke: Insights into Neural Glucose Metabolism and Endoplasmic Reticulum Stress Inhibition.
LncARSR promotes glioma tumor growth by mediating glycolysis through the STAT3/HK2 axis.
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming.
Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation.
Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1.
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands.
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Aging Is Associated With Impaired Postprandial Response of Skeletal Muscle Protein Synthesis to High-Intensity Muscle Contraction in Mice.
Lactate metabolism is essential in early-onset mitochondrial myopathy.
The Metabolic Changes between Monolayer (2D) and Three-Dimensional (3D) Culture Conditions in Human Mesenchymal Stem/Stromal Cells Derived from Adipose Tissue.
AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre-eclampsia.
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes.
Effect of chronic heat stress on the carbonylation of glycolytic enzymes in breast muscle and its correlation with the growth performance of broilers.
RPLP2 activates TLR4 in an autocrine manner and promotes HIF-1α-induced metabolic reprogramming in hepatocellular carcinoma.
Exosome-Related FTCD Facilitates M1 Macrophage Polarization and Impacts the Prognosis of Hepatocellular Carcinoma.
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Aspirin induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer.
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
A Photoannealed Granular Hydrogel Facilitating Hyaline Cartilage Regeneration via Improving Chondrogenic Phenotype.
Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis.
Effect of endurance training and PGC-1α overexpression on calculated lactate production volume during exercise based on blood lactate concentration.
Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy.
GCN5-mediated PKM2 acetylation participates in benzene-induced hematotoxicity through regulating glycolysis and inflammation via p-Stat3/IL17A axis.
Disrupting Circadian Rhythm via the PER1-HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer.
Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma.
Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.
Relocation of phosphofructokinases within epithelial cells is a novel event preceding breast cancer recurrence that accurately predicts patient outcomes.
The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
CTPS and IMPDH form cytoophidia in developmental thymocytes.
The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
L-Theanine affects intestinal mucosal immunity by regulating short-chain fatty acid metabolism under dietary fiber feeding.
A glycolytic shift in Schwann cells supports injured axons.
Synthesis and biological evaluation of novel 5,6,7-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents.
Mechanical regulation of glycolysis via cytoskeleton architecture.
Liver-targeted Nano-MitoPBN normalizes glucose metabolism by improving mitochondrial redox balance.
Protein recycling and limb muscle recovery after critical illness in slow- and fast-twitch limb muscle.
Click RNA for Rapid Capture and Identification of Intracellular MicroRNA Targets.
Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation.
Energy Metabolism in the Bone is Associated with Histomorphometric Changes in Rats with Hyperthyroidism.
High salt diet induces metabolic alterations in multiple biological processes of Dahl salt-sensitive rats.
Resveratrol inhibits VEGF-induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation.
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Dahuang Zhechong Pill Combined with Doxorubicin Induces Cell Death through Regulating Energy Metabolism in Human Hepatocellular Carcinoma Cells.
A large-scale targeted proteomics assay resource based on an in vitro human proteome.
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Testosterone differentially regulates targets of lipid and glucose metabolism in liver, muscle and adipose tissues of the testicular feminised mouse.
The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells.
The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.
Guo X, Lin Y, Jiang Y, Wang M, Li Y, Gao Y, Chen B, Bao Z, Tian H, Chu X, Zhang Z, Shao J, Zhang F, Wang H, Xuan J, Xu X, Zheng S
International journal of biological sciences 2026;22(3):1648-1673
International journal of biological sciences 2026;22(3):1648-1673
USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice.
Wu S, Cao R, Huang X, Feng Q, Zhang Y, Gao H, Tao B, Liang J, Yang W
PLoS biology 2026 Mar;24(3):e3003698
PLoS biology 2026 Mar;24(3):e3003698
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916
iScience 2026 Mar 20;29(3):114916
TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
Barone C, Wang R, Cooke S, Ng HP, Ferreira RS, Miranda HC, Qi X
Acta neuropathologica 2026 Mar 16;151(1)
Acta neuropathologica 2026 Mar 16;151(1)
N-nitrosodimethylamine increased glucose production by promoting hyperglycemia in hepatocyte via AMPK signaling pathway in vivo and in vitro.
Wang W, Xi S, Wang Y
Drug and chemical toxicology 2026 Jan 3;:1-12
Drug and chemical toxicology 2026 Jan 3;:1-12
Porcine epidemic diarrhea virus promotes viral replication via ROS/HIF-1α-mediated glycolysis.
Xu Y, Zhang J, Yin C, Liu L, Wang Z, Fu S, Fan R, Zhao Y, Miao J
Redox biology 2026 Feb;89:104008
Redox biology 2026 Feb;89:104008
High-Fat Diet Promotes Glycolysis in Hepatocellular Carcinoma by Suppressing Hepatic Kisspeptin Signaling in Mice.
Zhao R, Nie L, Shi Y, Jin L, Pan Y, Zhang X, Wang Z, He M, Zhang G, Yuan Q, Xia T, Wang S, Yang J, Yang W, Yuan D
Molecular carcinogenesis 2026 Feb;65(2):246-257
Molecular carcinogenesis 2026 Feb;65(2):246-257
Cancer-Associated fibroblasts regulate the development of cholangiocarcinoma through IL-6/STAT3/AKR1C3 signaling axis.
Huang TC, Feng WD, Fang GX, Zhang QH, Wei GY, Li CZ, Wang JM, Liu JF
Scientific reports 2026 Feb 25;16(1)
Scientific reports 2026 Feb 25;16(1)
The glycolytic enzyme PFKM promotes renal fibrosis by activating the NF-κB pathway via lactate-mediated H3K18 lactylation.
Chen Y, Wang W, Cheng M, Wei L, Sang Y, Gao Y, Zhang W, Zhang L, Dai R, Wang Y
Cellular and molecular life sciences : CMLS 2026 Feb 19;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 19;83(1)
AFP confers the resistance of lenvatinib in hepatocellular carcinoma by activating PI3K/AKT/LDHA signaling axis.
Xing W, Wang F, Feng S, Li X, Zhou Y, Wu H, Lin B, Dong X, Li M, Zhu M
Discover oncology 2026 Feb 16;17(1)
Discover oncology 2026 Feb 16;17(1)
Fructose-1,6-bisphosphate couples glycolytic activity to cell adhesion.
Hoffmann L, Duchmann M, Lazarow K, Huang YH, Lukas F, Lo WT, Feil R, Schmied C, Lehmann M, Lunn JE, Piazza I, von Kries JP, Haucke V, Maritzen T
Nature cell biology 2026 Apr;28(4):739-753
Nature cell biology 2026 Apr;28(4):739-753
Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats.
Ge H, Yan S, Yin M, Gao Y, Wang J, Wang Q, Xu G, Yang M
Pain research & management 2025;2025:9923147
Pain research & management 2025;2025:9923147
Artemether ameliorates type 1 diabetes mellitus by modulating glycolipid metabolism in skeletal muscle.
Dong Y, Fu Q, Zhang Y, Weng W, Han P, Cai Y, Sun H
American journal of translational research 2025;17(8):5871-5884
American journal of translational research 2025;17(8):5871-5884
Integrated Multilayer Omics Reveals the Underlying Mechanisms in Xylazine-Related Heart Injury in Rats.
Ou Y, Mai T, Wang N, Li Z, Chen Y, Zhao S
International journal of molecular sciences 2025 Sep 2;26(17)
International journal of molecular sciences 2025 Sep 2;26(17)
PKM2 alleviates mitochondrial oxidative stress and neuronal apoptosis through metabolic and non-metabolic pathways to protect SOD1(G93A) mice.
Zhang Z, Guo X, Liu Y, Ke P, Meng Y, Gu J, Hu L, Yuan Z, Duan R, Luo J, Xiao F
Free radical biology & medicine 2025 Oct;238:1-16
Free radical biology & medicine 2025 Oct;238:1-16
Astragaloside IV alleviates radiation-induced heart disease by regulating energy metabolism.
Li Q, Zhang S, Li Y, Yao N, Feng Y, Yang G, Wang Y, Dai S, Cheng S, Zhou T, Wang X, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157135
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157135
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1-Mediated Phosphoenolpyruvate Production.
Chen Z, Liao J, Zhu C, Chang R, Liang H, Ding Z, Huang Z, Chen X, Liang J, Zhang B
Cancer research 2025 Oct 15;85(20):3930-3948
Cancer research 2025 Oct 15;85(20):3930-3948
m(6)A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis.
Tan Z, Yang J, Chen Y, Zhu H, Liu X, Xu H, Meng Q, Xiao M, Tang R, Rong Z, Yu X, Liang C, Xu J
Cell death & disease 2025 Nov 3;16(1):784
Cell death & disease 2025 Nov 3;16(1):784
IL17A Mediates Glycolysis-Dependent Primary Angiogenesis and Exacerbates Ischemic Stroke Injury.
Xu Q, Lian Z, Ye Y, Wang J, Shafiq Z, Xiong X, Cai Q, Gu L
Molecular neurobiology 2025 Nov 25;63(1):169
Molecular neurobiology 2025 Nov 25;63(1):169
Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia.
Sun T, Yu H, Zhang D, Zhang D, Li D, Fu J
Redox biology 2025 May;82:103586
Redox biology 2025 May;82:103586
The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO(2) on Lactate Production in TM4 Cells.
Chang H, Zhao S, Lei Y, Hu Y, Yan Y, Song G
Journal of applied toxicology : JAT 2025 Mar;45(3):492-502
Journal of applied toxicology : JAT 2025 Mar;45(3):492-502
Knockdown of SESN2 Exacerbates Cerebral Ischemia-Reperfusion Injury Through Enhancing Glycolysis via the mTOR/HIF-1α Pathway.
Wang Z, Huang Y, Zhang Y, Zhu H, Amin MR, Chen R, Gu L, Xiong X
CNS neuroscience & therapeutics 2025 Mar;31(3):e70314
CNS neuroscience & therapeutics 2025 Mar;31(3):e70314
PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer.
Wu X, Wang B, Hou Y, Fang Y, Jiang Y, Song Y, Liu Y, Jin C
Biomolecules 2025 Mar 1;15(3)
Biomolecules 2025 Mar 1;15(3)
Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O(2)) during long-term Adipose-Derived Stem/Stromal cell culture.
Rybkowska P, Kawalec M, Dymkowska D, Radoszkiewicz K, Zabłocka B, Zabłocki K, Sarnowska A
European journal of cell biology 2025 Jun;104(2):151486
European journal of cell biology 2025 Jun;104(2):151486
Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia-reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle.
Hu Z, Deng N, Li Y, Bai Y, Lan X, Xiong T, Ding H, Liu X, Deng C
Chinese medicine 2025 Jul 7;20(1):108
Chinese medicine 2025 Jul 7;20(1):108
RB1 controls differentiation through positive regulation of phosphoglycerate mutases.
Kohno S, Okahashi N, Wan Y, Yu H, Takegami Y, Linn P, Nagatani N, Kitajima S, Kawada T, Matsuda F, Shimizu H, Takahashi C
Cell death & disease 2025 Jul 24;16(1):559
Cell death & disease 2025 Jul 24;16(1):559
PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate.
Lin P, Qi Y, Chu H, Wu H, Zhang Y, Huang X, Li C, Xu X, Gao H, Zeng R, Li G, Yang W
Nature communications 2025 Jul 22;16(1):6736
Nature communications 2025 Jul 22;16(1):6736
SESN2 mediates resistance training-induced improvements in exercise performance and energy metabolism in C57BL/6J mice.
Huang Y, Sun S, Yang X, Li X, Zhou Y, Liu S, Niu Y, Fu L
Experimental cell research 2025 Jul 1;450(1):114617
Experimental cell research 2025 Jul 1;450(1):114617
Baicalein suppresses inflammation and attenuates acute lung injury by inhibiting glycolysis via HIF‑1α signaling.
Liu Z, Zheng X, Li N, Wang Z
Molecular medicine reports 2025 Jan;31(1)
Molecular medicine reports 2025 Jan;31(1)
Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction.
Xu H, Wei K, Ni J, Deng X, Wang Y, Xiang T, Song F, Wang Q, Niu Y, Jiang F, Wang J, Sheng L, Dai J
Bone research 2025 Feb 14;13(1):23
Bone research 2025 Feb 14;13(1):23
Juglone targets MMP-1 to inhibit gastric cancer progression.
Zhou F, Xie Y, Li X, Peng P
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
m6A-mediated regulation of ECA39 promotes renal fibrosis in chronic kidney disease by enhancing glycolysis and epithelial-mesenchymal transition.
Tong Z, Zhao H, Cui C, Hong M, Ma Y, Sui L, Wang J, Yuan Q, Sun L
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119981
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119981
Activation of M1 macrophages promotes diabetic kidney disease by modulating glycolysis via HIF-1α-HK2 signaling pathway.
Pei X, Lu L, Huang Z, Wei Y, Li Y, Wang Q, Yang Y, Zhuang L, Jin G
Diabetology & metabolic syndrome 2025 Aug 29;17(1):362
Diabetology & metabolic syndrome 2025 Aug 29;17(1):362
Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome.
Yu F, Meng Y, Wang X, Chen J, He J, Yi X, He Y, Chen K
Cell reports 2025 Aug 26;44(8):116084
Cell reports 2025 Aug 26;44(8):116084
Fenofibrate Differently Affects the Heart's Morphology and Metabolism in Young and Old Rats.
Wrońska A, Kieżun J, Kmieć Z
International journal of molecular sciences 2025 Aug 20;26(16)
International journal of molecular sciences 2025 Aug 20;26(16)
TXNIP participates in the pathogenesis of PCOS by regulating glycolysis in granulosa cells.
Zhu R, Yang L, Li Y
Biochemical and biophysical research communications 2025 Aug 15;775:152149
Biochemical and biophysical research communications 2025 Aug 15;775:152149
Study on the mechanisms of defective spermatogenesis induced by TiO(2) NPs based on 3D blood-testis barrier microfluidic chip.
Dong R, Li L, Chang H, Song G, Liu S
Toxicology 2024 Sep;507:153888
Toxicology 2024 Sep;507:153888
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Dietary pectin and inulin: A promising adjuvant supplement for collagen-induced arthritis through gut microbiome restoration and CD4(+) T cell reconstitution.
Lou Y, Wen X, Song S, Zeng Y, Huang L, Xie Z, Shao T, Wen C
The Journal of nutritional biochemistry 2024 Nov;133:109699
The Journal of nutritional biochemistry 2024 Nov;133:109699
Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1.
Zhu G, Guan F, Li S, Zhang Q, Zhang X, Qin Y, Sun Z, Peng S, Cheng J, Li Y, Ren R, Fan T, Liu H
Molecular carcinogenesis 2024 May;63(5):897-911
Molecular carcinogenesis 2024 May;63(5):897-911
Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Liu J, Wei AH, Liu TT, Ji XH, Zhang Y, Yan F, Chen MX, Hu JB, Zhou SY, Shi JS, Jin H, Jin F
The FEBS journal 2024 May;291(10):2221-2241
The FEBS journal 2024 May;291(10):2221-2241
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Wang R, Min Q, Guo Y, Zhou Y, Zhang X, Wang D, Gao Y, Wei L
iScience 2024 Mar 15;27(3):109246
iScience 2024 Mar 15;27(3):109246
Physiological and molecular predictors of cycling sprint performance.
Galvan-Alvarez V, Gallego-Selles A, Martinez-Canton M, Perez-Suarez I, Garcia-Gonzalez E, Martin-Rincon M, Calbet JAL
Scandinavian journal of medicine & science in sports 2024 Jan;34(1):e14545
Scandinavian journal of medicine & science in sports 2024 Jan;34(1):e14545
Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands.
Buss LG, Rheinheimer BA, Limesand KH
Scientific reports 2024 Jan 8;14(1):845
Scientific reports 2024 Jan 8;14(1):845
Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling.
Cong Y, Cui X, Shi Y, Pan X, Huang K, Geng Z, Xu P, Ge L, Zhu J, Xu J, Jia X
Molecular and cellular biochemistry 2024 Dec;479(12):3405-3424
Molecular and cellular biochemistry 2024 Dec;479(12):3405-3424
Proteomic analysis of mouse liver lesions at all three stages of Echinococcus granulosus infection.
Jiang N, Chen Y, Li T, Sun Y, Su Y, Wang Y, Shen Y, Cao J
PLoS neglected tropical diseases 2024 Dec;18(12):e0012659
PLoS neglected tropical diseases 2024 Dec;18(12):e0012659
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Zur Nedden S, Safari MS, Weber D, Kuenkel L, Garmsiri C, Lang L, Orset C, Freret T, Haelewyn B, Hotze M, Kwiatkowski M, Sarg B, Faserl K, Savic D, Skvortsova II, Krogsdam A, Carollo S, Trajanoski Z, Oberacher H, Zlotek D, Ostermaier F, Cameron A, Baier G, Baier-Bitterlich G
Metabolism: clinical and experimental 2024 Dec;161:156039
Metabolism: clinical and experimental 2024 Dec;161:156039
Dynamic changes of protein lactylation and their correlations with the glycolytic process during the postmortem acidification of broiler breast.
Wang Z, Xing T, Zhang L, Zhao L, Gao F
Poultry science 2024 Dec;103(12):104354
Poultry science 2024 Dec;103(12):104354
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia.
Sun T, Yu H, Zhang D, Li D, Fu J
Respiratory research 2024 Dec 26;25(1):443
Respiratory research 2024 Dec 26;25(1):443
Neuroprotective Potential of Nitroglycerin in Ischemic Stroke: Insights into Neural Glucose Metabolism and Endoplasmic Reticulum Stress Inhibition.
Jiang S, Ding Y, Wang H, Kim E, Geng X
Journal of the American Heart Association 2024 Dec 17;13(24):e035382
Journal of the American Heart Association 2024 Dec 17;13(24):e035382
LncARSR promotes glioma tumor growth by mediating glycolysis through the STAT3/HK2 axis.
Tian Z, Dai Q, Liu B, Lin H, Ou H
Cytokine 2024 Aug;180:156663
Cytokine 2024 Aug;180:156663
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Sun X, He L, Liu H, Thorne RF, Zeng T, Liu L, Zhang B, He M, Huang Y, Li M, Gao E, Ma M, Cheng C, Meng F, Lang C, Li H, Xiong W, Pan S, Ren D, Dang B, Yang Y, Wu M, Liu L
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming.
Chen Y, Yan H, Yan L, Wang X, Che X, Hou K, Yang Y, Li X, Li Y, Zhang Y, Hu X
Cell death & disease 2023 Sep 20;14(9):617
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British journal of pharmacology 2023 Oct;180(19):2577-2598
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 55028-1-AP(PFKM antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PFKM antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PFKM. This antibody recognizes human,mouse,rat antigen. The PFKM antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
